Literature DB >> 25217087

[Successful treatment of Bowen disease with ingenol mebutate].

S A Braun1, B Homey, P A Gerber.   

Abstract

Ingenol mebutate is a novel cytotoxic drug extracted from the plant Euphorbia peplus. Since November 2012 it is approved in Germany for the treatment of superficial actinic keratoses. We report the successful treatment of Bowen disease with ingenol mebutate in a patient being treated with the multikinase inhibitor sunitinib for to metastatic clear cell renal carcinoma.

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Year:  2014        PMID： 25217087     DOI： 10.1007/s00105-014-3509-5

Source DB:  PubMed          Journal:  Hautarzt        ISSN： 0017-8470            Impact factor:   0.751


  7 in total

Review 1.  Dual mechanism of action of ingenol mebutate gel for topical treatment of actinic keratoses: rapid lesion necrosis followed by lesion-specific immune response.

Authors:  Robert H Rosen; Aditya K Gupta; Stephen K Tyring
Journal:  J Am Acad Dermatol       Date:  2011-11-04       Impact factor: 11.527

2.  Home treatment of skin cancer and solar keratoses.

Authors:  A C Green; G L Beardmore
Journal:  Australas J Dermatol       Date:  1988       Impact factor: 2.875

3.  Synthesis, biological evaluation and SAR of 3-benzoates of ingenol for treatment of actinic keratosis and non-melanoma skin cancer.

Authors:  Gunnar Grue-Sørensen; Xifu Liang; Kristoffer Månsson; Per Vedsø; Morten Dahl Sørensen; Anke Soor; Martin Stahlhut; Malene Bertelsen; Karen Margrethe Engell; Thomas Högberg
Journal:  Bioorg Med Chem Lett       Date:  2013-12-04       Impact factor: 2.823

4.  The sap from Euphorbia peplus is effective against human nonmelanoma skin cancers.

Authors:  J R Ramsay; A Suhrbier; J H Aylward; S Ogbourne; S-J Cozzi; M G Poulsen; K C Baumann; P Welburn; G L Redlich; P G Parsons
Journal:  Br J Dermatol       Date:  2011-01-27       Impact factor: 9.302

5.  Ingenol mebutate gel for actinic keratosis.

Authors:  Mark Lebwohl; Neil Swanson; Lawrence L Anderson; Anita Melgaard; Zhenyi Xu; Brian Berman
Journal:  N Engl J Med       Date:  2012-03-15       Impact factor: 91.245

6.  Ingenol mebutate: induced cell death patterns in normal and cancer epithelial cells.

Authors:  Martin Stahlhut; Malene Bertelsen; Maria Hoyer-Hansen; Nannette Svendsen; Andre H Eriksson; Janet M Lord; Dagmar Scheel-Toellner; Stephen P Young; John R Zibert
Journal:  J Drugs Dermatol       Date:  2012-10       Impact factor: 2.114

7.  Recurrent in situ melanoma successfully treated with ingenol mebutate.

Authors:  Marion Mansuy; Nazli Nikkels-Tassoudji; Jorge E Arrese; Andree Rorive; Arjen F Nikkels
Journal:  Dermatol Ther (Heidelb)       Date:  2014-04-02
  7 in total
  1 in total

1.  Comparison of the Treatment Outcomes of Photodynamic Therapy and Ingenol Mebutate in Bowen's Disease: A Retrospective Observational Study.

Authors:  Ji Hae An; Jung U Shin; Hyun Jung Kim; Hee Jung Lee; Moon Soo Yoon; Dong Hyun Kim
Journal:  Ann Dermatol       Date:  2019-12-27       Impact factor: 1.444
  1 in total

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