Literature DB >> 25217058

Why brain death is considered death and why there should be no confusion.

Christopher M Burkle1, Richard R Sharp2, Eelco F Wijdicks2.   

Abstract

Neurologic determination of brain death is a complex assessment that may be misunderstood by nonspecialists and families. Recent guidelines clarify how to proceed with such an examination and are available to physicians, with the time of death in adults and children being determined by the last defining test-the apnea test. This core principle in neurology has been challenged recently in court and resulted in an unprecedented continuation of care in a 13-year-old child declared dead. This review comments on the medical, legal, and ethical quandaries introduced by this case and highlights the major elements of consensus on matters related to brain death that have been forged over 3 decades of sustained medical and societal debate. A clear appreciation by physicians and the public of the diagnostic determination of death following loss of brain function will help to prevent similar conflicts from occurring in the future.
© 2014 American Academy of Neurology.

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Year:  2014        PMID: 25217058      PMCID: PMC4206160          DOI: 10.1212/WNL.0000000000000883

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  7 in total

1.  An act...relating to death and declaring the urgency thereof, to take effect immediately. Approved 27 Sep 1974.

Authors: 
Journal:  Wests Annot Calif Codes Calif       Date:  1974

2.  Brain death in children: why does it have to be so complicated?

Authors:  Eelco F M Wijdicks; Wade S Smith
Journal:  Ann Neurol       Date:  2012-04       Impact factor: 10.422

3.  Evidence-based guideline update: determining brain death in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology.

Authors:  Eelco F M Wijdicks; Panayiotis N Varelas; Gary S Gronseth; David M Greer
Journal:  Neurology       Date:  2010-06-08       Impact factor: 9.910

Review 4.  Brain death and the courts.

Authors:  Christopher M Burkle; Agnes M Schipper; Eelco F M Wijdicks
Journal:  Neurology       Date:  2011-03-01       Impact factor: 9.910

Review 5.  Controversies in defining and determining death in critical care.

Authors:  James L Bernat
Journal:  Nat Rev Neurol       Date:  2013-02-19       Impact factor: 42.937

6.  Guidelines for the determination of brain death in infants and children: an update of the 1987 Task Force recommendations.

Authors:  Thomas A Nakagawa; Stephen Ashwal; Mudit Mathur; Mohan R Mysore; Derek Bruce; Edward E Conway; Susan E Duthie; Shannon Hamrick; Rick Harrison; Andrea M Kline; Daniel J Lebovitz; Maureen A Madden; Vicki L Montgomery; Jeffrey M Perlman; Nancy Rollins; Sam D Shemie; Amit Vohra; Jacqueline A Williams-Phillips
Journal:  Crit Care Med       Date:  2011-09       Impact factor: 7.598

7.  A family's request for complementary medicine after patient brain death.

Authors:  Arthur Isak Applbaum; Jon C Tilburt; Michael T Collins; David Wendler
Journal:  JAMA       Date:  2008-05-14       Impact factor: 56.272

  7 in total
  16 in total

Review 1.  The Relevance of Irreversible Loss of Brain Function as a Reliable Sign of Death.

Authors:  Stephan A Brandt; Heinz Angstwurm
Journal:  Dtsch Arztebl Int       Date:  2018-10-12       Impact factor: 5.594

2.  Medicolegal Complications of Apnoea Testing for Determination of Brain Death.

Authors:  Ariane Lewis; David Greer
Journal:  J Bioeth Inq       Date:  2018-07-06       Impact factor: 1.352

Review 3.  Disputes in the Declaration of Brain Death: A Case Illustration.

Authors:  Eleanor Peterson
Journal:  J Pediatr Intensive Care       Date:  2017-06-27

Review 4.  Current controversies in brain death determination.

Authors:  Ariane Lewis; David Greer
Journal:  Nat Rev Neurol       Date:  2017-05-26       Impact factor: 42.937

Review 5.  When Brain Death Belies Belief.

Authors:  Greg Yanke; Mohamed Y Rady; Joseph L Verheijde
Journal:  J Relig Health       Date:  2016-12

6.  [Non-heart-beating donors are ineligible].

Authors:  W Heide
Journal:  Nervenarzt       Date:  2016-02       Impact factor: 1.214

7.  Bereavement interventions to support informal caregivers in the intensive care unit: a systematic review.

Authors:  Amanda Roze des Ordons; Kirsten M Fiest; Stephana J Moss; Krista Wollny; Therese G Poulin; Deborah J Cook; Henry T Stelfox
Journal:  BMC Palliat Care       Date:  2021-05-12       Impact factor: 3.234

Review 8.  Bioethics, Religion, and Public Policy: Intersections, Interactions, and Solutions.

Authors:  Peter A Kahn
Journal:  J Relig Health       Date:  2016-10

9.  Informed consent for the diagnosis of brain death: a conceptual argument.

Authors:  Osamu Muramoto
Journal:  Philos Ethics Humanit Med       Date:  2016-10-13       Impact factor: 2.464

10.  Does the Uniform Determination of Death Act Need to Be Revised?

Authors:  Doyen Nguyen
Journal:  Linacre Q       Date:  2020-06-02
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