Yaron Arbel1, Yacov Shacham2, Ariel Finkelstein2, Amir Halkin2, Assi Milwidsky3, Shlomo Berliner3, Tomer Ziv-Baran4, Miri Revivo2, Itzhak Herz2, Gad Keren2, Shmuel Banai2. 1. Department of Cardiology, Tel Aviv Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: yarona@tlvmc.gov.il. 2. Department of Cardiology, Tel Aviv Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. 3. Department of Internal Medicine "D+E", Tel Aviv Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. 4. Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University.
Abstract
INTRODUCTION: High RDW values are associated with adverse prognosis in many clinical conditions including short and medium term outcome of patients with ST Elevation Myocardial Infarction (STEMI). The aim of the present study was to evaluate the association between RDW and long term mortality in STEMI patients undergoing primary angioplasty (PPCI). MATERIAL AND METHODS: A cohort of 535 STEMI patients undergoing PPCI were divided into two groups (RDW > 14%, RDW ≤ 14%) using CHAID and CART methods. The association between RDW and 5-year all-cause mortality was assessed using Cox's proportional hazards analysis. RESULTS: A total of 37 patients died during follow up of 5 years (mean: 1059, median: 1013, range 2-2130 days). RDW > 14% was associated with increased risk of all-cause mortality (HR = 5, CI 95% 2.7- 9.9, p < 0.001). In multivariate analysis, RDW > 14 remained significantly associated with increased risk for all-cause mortality (HR = 3.8, CI 95% 1.8- 7.99, p < 0.001). Patients with RDW above 14% did not have lower ejection fraction, higher CPK or more conventional risk factors. CONCLUSION: RDW value above 14 is independently associated with increased long term all-cause mortality in patients with STEMI undergoing PPCI.
INTRODUCTION: High RDW values are associated with adverse prognosis in many clinical conditions including short and medium term outcome of patients with ST Elevation Myocardial Infarction (STEMI). The aim of the present study was to evaluate the association between RDW and long term mortality in STEMI patients undergoing primary angioplasty (PPCI). MATERIAL AND METHODS: A cohort of 535 STEMI patients undergoing PPCI were divided into two groups (RDW > 14%, RDW ≤ 14%) using CHAID and CART methods. The association between RDW and 5-year all-cause mortality was assessed using Cox's proportional hazards analysis. RESULTS: A total of 37 patients died during follow up of 5 years (mean: 1059, median: 1013, range 2-2130 days). RDW > 14% was associated with increased risk of all-cause mortality (HR = 5, CI 95% 2.7- 9.9, p < 0.001). In multivariate analysis, RDW > 14 remained significantly associated with increased risk for all-cause mortality (HR = 3.8, CI 95% 1.8- 7.99, p < 0.001). Patients with RDW above 14% did not have lower ejection fraction, higher CPK or more conventional risk factors. CONCLUSION: RDW value above 14 is independently associated with increased long term all-cause mortality in patients with STEMI undergoing PPCI.
Authors: Qi Liang; Xin-Jun Lei; Hong-Bing Li; Yang-Rong Yin; Jie Ren; Li-Hong Fan; Xin Huang; Zu-Yi Yuan Journal: Nan Fang Yi Ke Da Xue Xue Bao Date: 2017-08-20
Authors: Mi-Hyang Jung; Dong Il Shin; Ik Jun Choi; Suk Min Seo; Sooa Choi; Mahn Won Park; Pum-Joon Kim; Sang Hong Baek; Ki-Bae Seung Journal: Yonsei Med J Date: 2016-05 Impact factor: 2.759