Tiara Ratz1, Linda E Dean2, Fabiola Atzeni1, Christopher Reeks2, Gary J Macfarlane2, Tatiana V Macfarlane3. 1. Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, UK, Department of Public Health, University of Bremen, Bremen, Germany, Rheumatology Unit, L. Sacco University Hospital, Milan, Italy and University of Aberdeen Dental School and Hospital, Aberdeen, UK. Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, UK, Department of Public Health, University of Bremen, Bremen, Germany, Rheumatology Unit, L. Sacco University Hospital, Milan, Italy and University of Aberdeen Dental School and Hospital, Aberdeen, UK. 2. Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, UK, Department of Public Health, University of Bremen, Bremen, Germany, Rheumatology Unit, L. Sacco University Hospital, Milan, Italy and University of Aberdeen Dental School and Hospital, Aberdeen, UK. 3. Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, UK, Department of Public Health, University of Bremen, Bremen, Germany, Rheumatology Unit, L. Sacco University Hospital, Milan, Italy and University of Aberdeen Dental School and Hospital, Aberdeen, UK. tatiana.macfarlane@abdn.ac.uk.
Abstract
OBJECTIVE: The aim of this study was to examine the link between AS and periodontitis. METHODS: Medline, Embase, AMED, CINAHL, Web of Science and Google Scholar were searched to identify eligible studies that were selected and reviewed independently by at least two authors. RESULTS: Six case-control studies were included in the review. Study size ranged from 90 to 40 926 participants. The prevalence of periodontitis ranged from 38% to 88% in AS patients and from 26% to 71% in controls. As there was low-level heterogeneity (I(2) = 13%), using fixed effects analysis the overall pooled estimate of the odds ratios for periodontitis was 1.85 (95% CI 1.72, 1.98). There was no evidence of publication bias. CONCLUSION: The results led to the need for a further large study with sufficient statistical power to detect the desired effect size, taking into account potential confounding factors and using validated measures of AS and periodontitis.
OBJECTIVE: The aim of this study was to examine the link between AS and periodontitis. METHODS: Medline, Embase, AMED, CINAHL, Web of Science and Google Scholar were searched to identify eligible studies that were selected and reviewed independently by at least two authors. RESULTS: Six case-control studies were included in the review. Study size ranged from 90 to 40 926 participants. The prevalence of periodontitis ranged from 38% to 88% in AS patients and from 26% to 71% in controls. As there was low-level heterogeneity (I(2) = 13%), using fixed effects analysis the overall pooled estimate of the odds ratios for periodontitis was 1.85 (95% CI 1.72, 1.98). There was no evidence of publication bias. CONCLUSION: The results led to the need for a further large study with sufficient statistical power to detect the desired effect size, taking into account potential confounding factors and using validated measures of AS and periodontitis.
Authors: Dirk Ziebolz; David Douglas; Donya Douglas; Jan Schmickler; Daniel Patschan; Gerhard A Müller; Rainer Haak; Jana Schmidt; Gerhard Schmalz; Susann Patschan Journal: Rheumatol Int Date: 2018-03-20 Impact factor: 2.631
Authors: Gerhard Schmalz; Donya Douglas; David Douglas; Susann Patschan; Daniel Patschan; Gerhard A Müller; Rainer Haak; Jan Schmickler; Dirk Ziebolz Journal: Clin Oral Investig Date: 2018-02-07 Impact factor: 3.573
Authors: Wilson Bautista-Molano; Desirée van der Heijde; Robert Landewé; Gloria I Lafaurie; Juliette de Ávila; Rafael Valle-Oñate; Consuelo Romero-Sanchez Journal: RMD Open Date: 2017-12-10