| Literature DB >> 2521242 |
J Van Snick1, A Goethals, J C Renauld, E Van Roost, C Uyttenhove, M R Rubira, R L Moritz, R J Simpson.
Abstract
Recently, we described a murine helper T cell-derived molecule with T cell growth factor activity that is functionally and structurally distinct from IL-2, IL-4, and other known growth factors. This molecule, designated P40, was identified as a glycoprotein capable of supporting antigen-independent growth of certain helper T cell clones. Here, we report the cloning and expression of a cDNA for this new growth factor. The predicted mature protein is a cationic cysteine-rich polypeptide of 14 kD without significant homology to previously sequenced proteins.Entities:
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Year: 1989 PMID： 2521242 PMCID： PMC2189178 DOI： 10.1084/jem.169.1.363
Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307