Literature DB >> 25211167

SmI2-H2O-mediated 5-exo/6-exo lactone radical cyclisation cascades.

Irem Yalavac1, Sarah E Lyons, Michael R Webb, David J Procter.   

Abstract

The SmI2-H2O reagent system mediates challenging 5-exo/6-exo lactone radical cascade cyclisations that deliver carbo[5.4.0]bicyclic motifs in a diastereoselective, one-pot process that establish two new carbocyclic rings and four stereocentres.

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Year:  2014        PMID： 25211167     DOI： 10.1039/c4cc05404k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Selective Synthesis of Cyclooctanoids by Radical Cyclization of Seven-Membered Lactones: Neutron Diffraction Study of the Stereoselective Deuteration of a Chiral Organosamarium Intermediate.

Authors:  Xavier Just-Baringo; Jemma Clark; Matthias J Gutmann; David J Procter
Journal:  Angew Chem Int Ed Engl       Date:  2016-09-07       Impact factor: 15.336

2.  Copper-Catalyzed Double Additions and Radical Cyclization Cascades in the Re-Engineering of the Antibacterial Pleuromutilin.

Authors:  Rebecca E Ruscoe; Neal J Fazakerley; Huanming Huang; Sabine Flitsch; David J Procter
Journal:  Chemistry       Date:  2015-11-26       Impact factor: 5.236
  2 in total

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