Literature DB >> 2521091

Brain iron in progressive supranuclear palsy: clinical, magnetic resonance imaging, and neuropathological findings.

C E Coffey1, S Alston, E R Heinz, P C Burger.   

Abstract

A patient with progressive supranuclear palsy demonstrated a region-specific decrease in T2 signal during high-field-strength brain magnetic resonance imaging. At autopsy the T2-signal hypointensity was found to correspond topographically to increased deposition of ferric iron. The potential clinical, radiologic, and pathophysiologic implications of these findings are discussed.

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Year:  1989        PMID: 2521091     DOI: 10.1176/jnp.1.4.400

Source DB:  PubMed          Journal:  J Neuropsychiatry Clin Neurosci        ISSN: 0895-0172            Impact factor:   2.198


  3 in total

1.  Iron in neurodegenerative disorders.

Authors:  D. Berg; G. Becker; P. Riederer; O. Riess
Journal:  Neurotox Res       Date:  2002 Nov-Dec       Impact factor: 3.911

2.  Progressive supranuclear palsy: MRI and pathological findings.

Authors:  A Yagishita; M Oda
Journal:  Neuroradiology       Date:  1996-05       Impact factor: 2.804

3.  A delicate balance: Iron metabolism and diseases of the brain.

Authors:  Dominic Hare; Scott Ayton; Ashley Bush; Peng Lei
Journal:  Front Aging Neurosci       Date:  2013-07-18       Impact factor: 5.750

  3 in total

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