Literature DB >> 25208434

Successful implantation of a left ventricular assist device in a patient with heparin-induced thrombocytopenia and thrombosis.

Cassandra Garland, David Somogyi.   

Abstract

We report the case of a 27-year-old woman with signs of heparin-induced thrombocytopenia and thrombosis (HITT) and left heart failure presenting for urgent implantation of a left ventricular assist device (LVAD). HITT can occur in 4.2-6.1% of patients with LVADs. If the patient remains hemodynamically stable, implantation can be delayed for several months until the heparin/PF-4 antibodies decline allowing the use of heparin on cardiopulmonary bypass, However, in most cases related to cardiogenic shock, surgery cannot be delayed. We present the case of a patient who underwent implantation of a HeartMate II LVAD and discuss management strategy using bivalirudin during cardiopulmonary bypass.

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Year:  2014        PMID: 25208434      PMCID: PMC4566427     

Source DB:  PubMed          Journal:  J Extra Corpor Technol        ISSN: 0022-1058


  4 in total

1.  Bivalirudin during cardiopulmonary bypass in patients with previous or acute heparin-induced thrombocytopenia and heparin antibodies: results of the CHOOSE-ON trial.

Authors:  Andreas Koster; Cornelius M Dyke; Gabriel Aldea; Nicholas G Smedira; Harry L McCarthy; Solomon Aronson; Roland Hetzer; Edwin Avery; Bruce Spiess; A Michael Lincoff
Journal:  Ann Thorac Surg       Date:  2007-02       Impact factor: 4.330

2.  Tolerance to intravenous heparin in patients with delayed-type hypersensitivity to heparins: a prospective study.

Authors:  Zeno Gaigl; Petra Pfeuffer; Petra Raith; Eva-B Bröcker; Axel Trautmann
Journal:  Br J Haematol       Date:  2005-02       Impact factor: 6.998

3.  Assessment of hemostatic activation during cardiopulmonary bypass for coronary artery bypass grafting with bivalirudin: results of a pilot study.

Authors:  Andreas Koster; Ruhi Yeter; Semih Buz; Hermann Kuppe; Roland Hetzer; A Michael Lincoff; Cornelius M Dyke; Nicholas G Smedira; Bruce Spiess
Journal:  J Thorac Cardiovasc Surg       Date:  2005-06       Impact factor: 5.209

Review 4.  Heparin-induced thrombocytopenia. A contemporary clinical approach to diagnosis and management.

Authors:  Eduard Shantsila; Gregory Y H Lip; Beng H Chong
Journal:  Chest       Date:  2009-06       Impact factor: 9.410

  4 in total
  3 in total

1.  Bivalirudin as an Alternative Anticoagulant for Cardiopulmonary Bypass During Adult Cardiac Surgery-A Change in Practice.

Authors:  Peter Gatt; Samuel Anthony Galea; Walter Busuttil; Charles Grima; Jeffrey Muscat; Yvette Farrugia
Journal:  J Extra Corpor Technol       Date:  2017-03

2.  Bivalirudin Anticoagulation for a Pediatric Patient with Heparin-Induced Thrombocytopenia and Thrombosis Requiring Cardiopulmonary Bypass for Ventricular Assist Device Placement.

Authors:  Katie H Faella; David Whiting; Francis Fynn-Thompson; Gregory S Matte
Journal:  J Extra Corpor Technol       Date:  2016-03

3.  The use of cangrelor with heparin for left ventricular assist device implantation in a patient with acute heparin-induced thrombocytopenia.

Authors:  Yan K Gernhofer; Michael Ross; Swapnil Khoche; Victor Pretorius
Journal:  J Cardiothorac Surg       Date:  2018-04-17       Impact factor: 1.637

  3 in total

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