Literature DB >> 25207899

Research advances on TCM anti-tumor effects and the molecular mechanisms.

Xiaochun Qiu, Jack Jia1.   

Abstract

With unceasingly deep researches on tumor cytology and molecular biology in recent years, it has been recognized that tumor is not only the outcome of occurrence and progress of cell proliferative disorders and abnormal differentiation, but also closely related to abnormality of apoptosis. Since traditional Chinese medicine (TCM) is easy to obtain and exhibits significant antitumor effects accompanied with less toxic and side effects, it has already become a hotspot for cancer researches. This article is to overview TCM's antitumor effects and to summarize the underlying molecular mechanisms.

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Year:  2014        PMID: 25207899     DOI: 10.4103/0973-1482.139744

Source DB:  PubMed          Journal:  J Cancer Res Ther        ISSN: 1998-4138            Impact factor:   1.805


  5 in total

1.  Alpinia katsumadai Hayata induces growth inhibition and autophagy‑related apoptosis by regulating the AMPK and Akt/mTOR/p70S6K signaling pathways in cancer cells.

Authors:  Weixiao An; Yuxi Zhang; Honglin Lai; Yangyang Zhang; Hongmei Zhang; Ge Zhao; Minghua Liu; Yang Li; Xiukun Lin; Shousong Cao
Journal:  Oncol Rep       Date:  2022-06-22       Impact factor: 4.136

2.  Molecular Mechanisms Underlying the Inhibitory Effects of Qingzaojiufei Decoction on Tumor Growth in Lewis Lung Carcinoma.

Authors:  Bin Xie; Xiong Xie; Bin Rao; Shengzhang Liu; Hongning Liu
Journal:  Integr Cancer Ther       Date:  2017-02-01       Impact factor: 3.279

3.  Investigation of the mechanism of the anti-cancer effects of Astragalus propinquus Schischkin and Pinellia pedatisecta Schott (A&P) on melanoma via network pharmacology and experimental verification.

Authors:  Fang Wang; Juan Bai; Feng Li; Jing Liu; Yanli Wang; Ning Li; Yaqi Wang; Jin Xu; Wanbao Liu; Liting Xu; Lin Chen
Journal:  Front Pharmacol       Date:  2022-08-12       Impact factor: 5.988

4.  Tibetan medicine salidroside improves host anti-mycobacterial response by boosting inflammatory cytokine production in zebrafish.

Authors:  Shumei He; Hongyan Fan; Bin Sun; Meipan Yang; Hongxu Liu; Jianwei Yang; Jianxin Liu; Sizhu Luo; Zihan Chen; Jing Zhou; Lu Xia; Shulin Zhang; Bo Yan
Journal:  Front Pharmacol       Date:  2022-08-31       Impact factor: 5.988

5.  N-Butanol Subfraction of Brassica Rapa L. Promotes Reactive Oxygen Species Production and Induces Apoptosis of A549 Lung Adenocarcinoma Cells via Mitochondria-Dependent Pathway.

Authors:  Adila Aipire; Qiuyan Chen; Shanshan Cai; Jinyu Li; Changshuang Fu; Tianlei Ying; Jun Lu; Jinyao Li
Journal:  Molecules       Date:  2018-07-11       Impact factor: 4.411

  5 in total

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