Literature DB >> 25207897

Evaluation of sodium cantharidinate/vitamin B6 in the treatment of primary liver cancer.

Hejun Shao, Guohu Hong, Xinhua Luo1.   

Abstract

OBJECTIVE: The present study evaluated the treatment effectiveness of sodium cantharidinate/vitamin B6 in patient with middle/late stage primary liver cancer.
MATERIALS AND METHODS: A 3-month follow-up study on 104 patients with primary liver cancer was carried out. Regular medication treatment was applied to 41 patients and sodium cantharidinate/vitamin B6 combined with the regular medication was applied to 63 patients. The treatment effectiveness and prognosis were evaluated using the statistical methods.
RESULTS: At the end of the treatment, no significant difference was detected between the two groups; 1-month follow-up survey showed that in the treatment group, the death rate was lower, the treatment gain was maintained longer and the tumor morphology was maintained better, compared with the control group; 3-month follow-up study showed that there was not significance difference between the two groups.
CONCLUSION: Sodium cantharidinate/vitamin B6 might be used as auxiliary drug in patients with primary liver cancer and could improve the treatment outcomes for a short-term period.

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Year:  2014        PMID: 25207897     DOI: 10.4103/0973-1482.139770

Source DB:  PubMed          Journal:  J Cancer Res Ther        ISSN: 1998-4138            Impact factor:   1.805


  5 in total

Review 1.  Cancer Chemotherapy Specific to Acidic Nests.

Authors:  Hiroshi Kobayashi
Journal:  Cancers (Basel)       Date:  2017-04-20       Impact factor: 6.639

2.  Methyl-Cantharidimide Inhibits Growth of Human Hepatocellular Carcinoma Cells by Inducing Cell Cycle Arrest and Promoting Apoptosis.

Authors:  Xiangzhong Huang; Wen Xie; Xiaofan Yu; Caiyun Fan; Jin Wang; Yi Cao; Jianxiang Li
Journal:  Front Oncol       Date:  2019-11-15       Impact factor: 6.244

3.  Efficacy and Safety of Docetaxel and Sodium Cantharidinate Combination vs. Either Agent Alone as Second-Line Treatment for Advanced/Metastatic NSCLC With Wild-Type or Unknown EGFR Status: An Open-Label, Randomized Controlled, Prospective, Multi-Center Phase III Trial (Cando-L1).

Authors:  Lin Wu; Chao Deng; Hui Zhang; Jie Weng; Youhua Wu; Shan Zeng; Tiegang Tang; Peiguo Cao; Bo Qiu; Li Zhang; Huaxin Duan; Bing Zhang; Dong Zhang; Taotao Zhang; Chunhong Hu
Journal:  Front Oncol       Date:  2021-12-14       Impact factor: 6.244

4.  Efficacy and safety of sodium cantharidinate and vitamin B6 injection for the treatment of digestive system neoplasms: a meta-analysis of randomized controlled trials.

Authors:  Meirong Liu; Chunhong Xu; Yingying Sun
Journal:  Drug Des Devel Ther       Date:  2018-12-28       Impact factor: 4.162

5.  Effect of sodium cantharidinate/vitamin B6 injection on survival, liver function, immune function, and quality of life in patients with hepatocellular carcinoma: Protocol for a meta-analysis.

Authors:  Min Zhu; Xiujing Liu; Changhui Zhou; Juan Li
Journal:  Medicine (Baltimore)       Date:  2020-08-21       Impact factor: 1.817

  5 in total

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