Literature DB >> 25207876

Orbital mass secondary to acute lymphoblastic leukaemia in a child: a rare presentation.

Saadia R Chaudhry1, Andreas J Kreis, Helen C Underhill, Simon N Madge.   

Abstract

We report the case of a 3-year-old child, who presented with lid swelling which progressed to proptosis of the left eye. He also had systemic symptoms of fatigue and weight loss. An examination revealed hepatosplenomegaly and lymph node enlargement. Investigations showed a peripheral smear with blast cells, which were also revealed through a bone marrow biopsy. A CT scan showed a mass lesion in the left orbit that had infiltrated into the surrounding tissues. He was diagnosed with acute lymphoblastic leukaemia (ALL) with left-sided orbital mass secondary to it. Haematogenous masses in the orbit are commonly due to granulocytic sarcomas, which are usually associated with acute myelogenous leukaemia (AML), not ALL, and are rare especially when they precede systemic disease.

Entities:  

Keywords:  ALL; child; granulocytic sarcoma; orbital mass; proptosis

Mesh:

Substances:

Year:  2014        PMID: 25207876     DOI: 10.3109/01676830.2014.949791

Source DB:  PubMed          Journal:  Orbit        ISSN: 0167-6830


  4 in total

1.  Bilateral Ocular Exophthalmia - A Case of Atypical Acute Myeloblastic Leukemia in a Child.

Authors:  Réka Toth; Alina Grama; Cristina Maki; Mihaela Ioana Chinceșan
Journal:  J Crit Care Med (Targu Mures)       Date:  2020-11-07

2.  Orbital mass secondary to infantile acute lymphoblastic leukaemia.

Authors:  Ibtesham Tausif Hossain; Mariya Moosajee; Yassir Abou-Rayyah; Vesna Pavasovic
Journal:  BMJ Case Rep       Date:  2016-05-03

3.  Bilateral Proptosis in a Child: A Rare Presentation of Acute Lymphoblastic Leukemia.

Authors:  Pon Ramya Sivaperumal; Sneha Magatha Latha; Sowmiya Narayani; Julius Scott
Journal:  J Ophthalmic Vis Res       Date:  2018 Oct-Dec

4.  Unusual Presentation with Orbital Mass in a Child with Precursor B-Cell Acute Lymphoblastic Leukemia.

Authors:  Lalita Sathitsamitphong; Rungrote Natesirinilkul; Worawut Choeyprasert; Pimlak Charoenkwan
Journal:  Case Rep Hematol       Date:  2019-11-05
  4 in total

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