Kıvanç Ergen1, Hürrem Ince2, Halil Düzova3, Yunus Karakoç4, M Hanifi Emre3. 1. Department of Biophysics, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey. 2. Department of Chemistry, Faculty of Science and Literature, İstanbul Technical University, İstanbul, Turkey. 3. Department of Physiology, Faculty of Medicine, İnönü University, Malatya, Turkey. 4. Department of Biophysics, Faculty of Medicine, İnönü University, Malatya, Turkey.
Abstract
OBJECTIVE: Trace elements such as manganese (Mn), cobalt (Co) and chromium (Cr) play key roles in metabolic reactions and are important in many physiological enzymatic processes. In this study, we aimed to investigate the acute effects of moderate and strenuous running (treadmill) exercise on the levels of Mn, Co and Cr in the brain, liver, and spleen of trained rats. STUDY DESIGN: Animal experiment. MATERIAL AND METHODS: Twenty-one Wistar-Albino adult male rats were used in the study. Rats were grouped as control group (no mandated exercise; n=8), moderate exercise group (30 min exercise duration; n=7), and strenuous exercise group (60 min exercise duration; n=6). The levels of Mn, Co, and Cr in the frontal lobe, temporal lobe, brain stem, liver, and spleen were determined by atomic absorption spectrophotometer. RESULTS: Cr levels in liver of rats increased in parallel to the time course of running supporting the exercise training effect on the action of insulin. Compared to the control group, the level of Co significantly decreased in the brain stem of rats in the moderate exercise group (p=0.009) and in the frontal lobe of rats in the strenuous exercise group (p=0.004). In the strenuous exercise group, an examination of the brain stem revealed that the level of Mn significantly decreased (p=0.001), and levels of Co and Cr were apparently depleted to the extent that these elements were no longer detectable. CONCLUSION: A notable finding is that during or after single bout strenuous exercise, levels of Co decreased in the spleen and particularly decreased in the brain stem of regularly trained rats. From this study, it can be inferred that sportsmen should aware trace element disturbances among the body parts or depletion of some trace elements after single bout of chronic strenuous running exercise.
OBJECTIVE: Trace elements such as manganese (Mn), cobalt (Co) and chromium (Cr) play key roles in metabolic reactions and are important in many physiological enzymatic processes. In this study, we aimed to investigate the acute effects of moderate and strenuous running (treadmill) exercise on the levels of Mn, Co and Cr in the brain, liver, and spleen of trained rats. STUDY DESIGN: Animal experiment. MATERIAL AND METHODS: Twenty-one Wistar-Albino adult male rats were used in the study. Rats were grouped as control group (no mandated exercise; n=8), moderate exercise group (30 min exercise duration; n=7), and strenuous exercise group (60 min exercise duration; n=6). The levels of Mn, Co, and Cr in the frontal lobe, temporal lobe, brain stem, liver, and spleen were determined by atomic absorption spectrophotometer. RESULTS:Cr levels in liver of rats increased in parallel to the time course of running supporting the exercise training effect on the action of insulin. Compared to the control group, the level of Co significantly decreased in the brain stem of rats in the moderate exercise group (p=0.009) and in the frontal lobe of rats in the strenuous exercise group (p=0.004). In the strenuous exercise group, an examination of the brain stem revealed that the level of Mn significantly decreased (p=0.001), and levels of Co and Cr were apparently depleted to the extent that these elements were no longer detectable. CONCLUSION: A notable finding is that during or after single bout strenuous exercise, levels of Co decreased in the spleen and particularly decreased in the brain stem of regularly trained rats. From this study, it can be inferred that sportsmen should aware trace element disturbances among the body parts or depletion of some trace elements after single bout of chronic strenuous running exercise.
Authors: J L Chicharro; V Serrano; R Ureña; A M Gutierrez; A Carvajal; P Fernández-Hernando; A Lucía Journal: Br J Sports Med Date: 1999-06 Impact factor: 13.800
Authors: F D Brites; P A Evelson; M G Christiansen; M F Nicol; M J Basílico; R W Wikinski; S F Llesuy Journal: Clin Sci (Lond) Date: 1999-04 Impact factor: 6.124
Authors: Anatoly V Skalny; Irina P Zaitseva; Yordanka G Gluhcheva; Andrey A Skalny; Evgeny E Achkasov; Margarita G Skalnaya; Alexey A Tinkov Journal: J Appl Biomed Date: 2018-11-23 Impact factor: 1.797