Kelly E Gill1,2, Victoria Cressman3, Sarah Lucy Poe1,2, Sara Steinfeld1, Shelly Ben-David1,4, John G Keilp1, Holly Moore1,2, Lyn S Turkstra5, Cheryl Corcoran1,2. 1. Department of Psychiatry, Columbia University, New York, New York, USA. 2. Psychiatry, New York State Psychiatric Institute, New York, New York, USA. 3. Department of Psychiatry, New York Harbor Healthcare System, New York University School of Medicine, New York, New York, USA. 4. School of Social Work, New York University, New York, New York, USA. 5. Department of Communication Sciences and Disorders, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Abstract
AIM: Social cognition impairment is a hallmark of schizophrenia and contains multiple domains. The domain of social inference has been relatively understudied in schizophrenia and its risk states. METHODS: Social inference was assessed in 60 clinical high-risk (CHR) patients and 28 healthy control subjects, using the video social inference task. We hypothesized a deficit in social inference in CHR participants and examined predictive value for psychosis transition. RESULTS: Social inference was positively associated with increasing age. Social inference did not differ significantly between CHR patients and controls, or predict transition to psychosis. CONCLUSIONS: Few studies have examined social inference of individuals at clinical high risk for psychosis, and findings have been inconclusive. Additional studies using a variety of measures of social inference in CHR participants are recommended.
AIM: Social cognition impairment is a hallmark of schizophrenia and contains multiple domains. The domain of social inference has been relatively understudied in schizophrenia and its risk states. METHODS: Social inference was assessed in 60 clinical high-risk (CHR) patients and 28 healthy control subjects, using the video social inference task. We hypothesized a deficit in social inference in CHRparticipants and examined predictive value for psychosis transition. RESULTS: Social inference was positively associated with increasing age. Social inference did not differ significantly between CHRpatients and controls, or predict transition to psychosis. CONCLUSIONS: Few studies have examined social inference of individuals at clinical high risk for psychosis, and findings have been inconclusive. Additional studies using a variety of measures of social inference in CHRparticipants are recommended.
Authors: Louise Birkedal Glenthøj; Carsten Hjorthøj; Tina Dam Kristensen; Charlie Andrew Davidson; Merete Nordentoft Journal: NPJ Schizophr Date: 2017-05-08