| Literature DB >> 25203316 |
Marion Maurel1, Afshin Samali2, Eric Chevet3.
Abstract
Steatohepatitis is a cause of hepatocellular carcinoma development; however, the underlying mechanisms are poorly defined. In this issue of Cancer Cell, Nakagawa and colleagues demonstrate that activation of endoplasmic reticulum stress signaling is instrumental in the development of steatohepatitis and synergizes with proinflammatory pathways to promote hepatocarcinogenesis.Entities:
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Year: 2014 PMID: 25203316 DOI: 10.1016/j.ccr.2014.08.007
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743