Literature DB >> 25200601

Mean platelet volume as an inflammatory marker of chronic otitis media with effusion.

Battal Tahsin Somuk1, Harun Soyalıç2, Sema Koc3, Levent Gürbüzler2, Serkan Doğru4, Ahmet Eyibilen2.   

Abstract

OBJECTIVES: Our aim was to investigate whether mean platelet volume (MPV) may be utilized as an inflammatory marker of chronic otitis media with effusion (COME).
METHODS: Routine hemogram tests were performed preoperatively for 51 patients diagnosed with COME that were to receive ventilation tube insertion. Hemogram tests were performed on age-matched and sex-matched healthy controls (n=54). Moreover, by performing a chart review, white blood cell count (WBC), red blood cell count (RBC), hemoglobin (Hb), hematocrit (Hct), platelet (PLT), and mean platelet volume (MPV) values were compared between COME patients and controls.
RESULTS: A total of 51 COME patients were included in the study and 45.1% were male. The control group had 54 individuals and 51.9% were male. MPV (p=0.493) and platelet levels (p=0.336) for COME patients group were generally borderline higher than those measured for the control group, but this difference was not statistically significant.
CONCLUSION: No statistically significant differences were identified between pediatric patients diagnosed with COME and healthy controls in terms of WBC, RBC, Hb, Hct, PLT and MPV levels.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Mean platelet volume; Otitis media with effusion; Platelet activation

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Year:  2014        PMID: 25200601     DOI: 10.1016/j.ijporl.2014.08.037

Source DB:  PubMed          Journal:  Int J Pediatr Otorhinolaryngol        ISSN: 0165-5876            Impact factor:   1.675


  1 in total

1.  Trans-cortical vessels in the mouse temporal bulla bone are a means to recruit myeloid cells in chronic otitis media and limit peripheral leukogram changes.

Authors:  Ali Azar; Mahmood F Bhutta; Jorge Del-Pozo; Elspeth Milne; Michael Cheeseman
Journal:  Front Genet       Date:  2022-09-28       Impact factor: 4.772

  1 in total

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