| Literature DB >> 2519957 |
Abstract
Pulmonary intravascular macrophages (PIMs) have been recognized as the site of substantial uptake of blood-borne particles in the lungs of a number of domestic animal species. Concomitantly, there is a pronounced lung susceptibility to endotoxin in calves, goats, sheep, pigs, and cats. Hemodynamic changes and initial lung injury after endotoxin administration are mediated by arachidonic acid metabolites from a pulmonary source. A significant role of PIMs in regulating pulmonary hemodynamics is implicated.Entities:
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Year: 1989 PMID: 2519957 DOI: 10.1159/000163539
Source DB: PubMed Journal: Exp Cell Biol ISSN: 0304-3568