| Literature DB >> 25199012 |
A Chaiprasert1, S Srimuang2, N Tingtoy1, N Makhao2, P Sirirudeeporn2, N Tomnongdee2, O Theankeaw2, S Charoensook2, M Leechawengwongs2, T Prammananan2.
Abstract
The increasing incidence of multidrug-resistant tuberculosis (MDR-TB) and the emergence of extensively drug-resistant tuberculosis (XDR-TB) globally hamper the successful treatment and effective control of TB. Information on second-line drug susceptibility, which is of utmost importance for patient care, is still limited. This study demonstrates the susceptibilities of 1447 strains of MDR-TB, including 58 XDR-TB strains, isolated from Siriraj Hospital, Bangkok, Thailand, to aminoglycosides, fluoroquinolones, ethionamide (ETH), para-aminosalicylic acid (PAS) and linezolid. Results revealed that 93-94% of the MDR-TB strains were susceptible to aminoglycosides, 85-98% to fluoroquinolones, 78% to ETH, 85% to PAS and 99% to linezolid.Entities:
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Year: 2014 PMID： 25199012 DOI： 10.5588/ijtld.13.0197
Source DB: PubMed Journal: Int J Tuberc Lung Dis ISSN： 1027-3719 Impact factor: 2.373