| Literature DB >> 25198895 |
Reza Zolfaghari Emameh1, Leo Syrjänen, Harlan Barker, Claudiu T Supuran, Seppo Parkkila.
Abstract
Beta-carbonic anhydrases (β-CAs) have been recently reported to be present in many protozoan and metazoan species, whereas it is absent in mammals. In this review, we introduce β-CA from Drosophila melanogaster as a model enzyme for pesticide development. These enzymes can be targeted with various enzyme inhibitors, which can have deleterious effects on pathogenic and other harmful organisms. Therefore, β-CAs represent a new potential target to fight against Dipteran vectors and pests relevant to medicine, veterinary medicine, and agriculture.Entities:
Keywords: Carbonic anhydrase; Dipteran; Drosophila melanogaster; inhibitors; pesticides
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Year: 2014 PMID: 25198895 DOI: 10.3109/14756366.2014.944178
Source DB: PubMed Journal: J Enzyme Inhib Med Chem ISSN: 1475-6366 Impact factor: 5.051