Literature DB >> 25197406

Spindle cell rhabdomyosarcoma in the hypopharynx of an adult.

Ting-Ting Wu1, Qin-Ying Wang1, Shui-Hong Zhou1, Zhou-Jun Zheng2.   

Abstract

We herein present the first-reported case in the English-language literature of a spindle cell rhabdomyosarcoma in the hypopharynx of an adult. A 58-year-old male presented with a progressive, 7-month history of discomfort during swallowing, accompanied by hoarseness for 1 month. Computed tomography and magnetic resonance imaging revealed a tumor in the left pyriform sinus; frozen section evaluation suggested that it was rhabdomyosarcoma. The tumor was removed completely via left lateral cervical incision. Section margins were negative, and laryngeal function was preserved. The postoperative pathological results indicated spindle cell rhabdomyosarcoma. The patient received postoperative radiotherapy (6,000 cGy in 200 cGy fractions, delivered over 30 days). However, he was also required to undergo urgent tracheostomy due to severe laryngeal obstruction, precipitated by laryngeal edema, 3 months subsequent to radiotherapy. The patient was free of disease 25 months postoperatively but is still unable to close his tracheostomy.

Entities:  

Keywords:  Spindle cell rhabdomyosarcoma; adult; hypopharynx; radiotherapy

Mesh:

Year:  2014        PMID: 25197406      PMCID: PMC4152096     

Source DB:  PubMed          Journal:  Int J Clin Exp Pathol        ISSN: 1936-2625


  12 in total

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Review 3.  Pediatric rhabdomyosarcoma of the head and neck.

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4.  Spindle cell rhabdomyosarcoma in adults: clinicopathological and immunohistochemical analysis of seven new cases.

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Journal:  Am J Surg Pathol       Date:  2005-08       Impact factor: 6.394

6.  Epithelioid rhabdomyosarcoma: clinicopathologic analysis of 16 cases of a morphologically distinct variant of rhabdomyosarcoma.

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7.  Spindle cell rhabdomyosarcoma (so-called) in adults: report of two cases with emphasis on differential diagnosis.

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8.  Head and neck rhabdomyosarcoma in adults.

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9.  Spindle cell variants of embryonal rhabdomyosarcoma in the paratesticular region. A report of the Intergroup Rhabdomyosarcoma Study.

Authors:  I Leuschner; W A Newton; D Schmidt; N Sachs; L Asmar; A Hamoudi; D Harms; H M Maurer
Journal:  Am J Surg Pathol       Date:  1993-03       Impact factor: 6.394

10.  Paediatric head and neck malignancies in Ibadan, Nigeria.

Authors:  B F Adeyemi; B M Kolude; G O Ogun; E E U Akang
Journal:  Afr J Med Med Sci       Date:  2009-03
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  2 in total

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2.  Resilience Through Squamous Cell Carcinoma and Rhabdomyosarcoma of Oral Cavity: A Unique Case Report.

Authors:  Sidra Mumtaz Shaikh; Sobia Faisal; Iqbal A M Khyani; Bushra Sikandar
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  2 in total

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