Literature DB >> 25196680

Pharmacology and mechanisms of action of new oral anticoagulants.

Joe-Elie Salem1, Pierre Sabouret, Christian Funck-Brentano, Jean-Sebastien Hulot.   

Abstract

The new oral anticoagulants are announced as an important therapeutic revolution, particularly after their approval by authorities for stroke prevention in atrial fibrillation. However, the pharmacology of these new drugs is not homogeneous. In this review, we summarize the main pharmacological characteristics of the new direct anti-Xa and anti-IIa agents.
© 2014 Société Française de Pharmacologie et de Thérapeutique.

Entities:  

Keywords:  anticoagulant; apixaban; dabigatran; edoxaban; heparin; pharmacology; rivaroxaban

Mesh：

Substances：

Year:  2014        PMID： 25196680     DOI： 10.1111/fcp.12091

Source DB:  PubMed          Journal:  Fundam Clin Pharmacol        ISSN： 0767-3981            Impact factor:   2.748


  7 in total

Review 1.  Efficacy and safety of the target-specific oral anticoagulants for stroke prevention in atrial fibrillation: the real-life evidence.

Authors:  Vincenzo Russo; Anna Rago; Riccardo Proietti; Federica Di Meo; Andrea Antonio Papa; Paolo Calabrò; Antonio D'Onofrio; Gerardo Nigro; Ahmed AlTurki
Journal:  Ther Adv Drug Saf       Date:  2016-10-24

2.  Risk of hospitalised bleeding in comparisons of oral anticoagulant options for the primary treatment of venous thromboembolism.

Authors:  Pamela L Lutsey; Neil A Zakai; Richard F MacLehose; Faye L Norby; Rob F Walker; Nicholas S Roetker; Terrence J Adam; Alvaro Alonso
Journal:  Br J Haematol       Date:  2019-03-28       Impact factor: 6.998

3.  The Influence of ABCB1 (rs1045642 and rs4148738) Gene Polymorphisms on Rivaroxaban Pharmacokinetics in Patients Aged 80 Years and Older with Nonvalvular Atrial Fibrillation.

Authors:  Dmitry Sychev; Olga Ostroumova; Marina Cherniaeva; Nataliia Shakhgildian; Karin Mirzaev; Sherzod Abdullaev; Natalia Denisenko; Zhannet Sozaeva; Anastasia Kachanova; Svetlana Gorbatenkova; Vera Shastina
Journal:  High Blood Press Cardiovasc Prev       Date:  2022-08-12

4.  Massive intoxication with rivaroxaban, phenprocoumon, and diclofenac: A case report.

Authors:  Hella Pfeiffer; Larissa Herbst; Bernd Schwarze; Reinhold Eckstein; Volker Weisbach
Journal:  Medicine (Baltimore)       Date:  2016-11       Impact factor: 1.889

5.  ANMCO Position Paper: direct oral anticoagulants for stroke prevention in atrial fibrillation: clinical scenarios and future perspectives.

Authors:  Federico Nardi; Michele Massimo Gulizia; Furio Colivicchi; Maurizio Giuseppe Abrignani; Stefania Angela Di Fusco; Andrea Di Lenarda; Giuseppe Di Tano; Giovanna Geraci; Luigi Moschini; Carmine Riccio; Paolo Verdecchia; Iolanda Enea
Journal:  Eur Heart J Suppl       Date:  2017-05-02       Impact factor: 1.803

6.  Oral anticoagulation therapy and subsequent risk of venous thromboembolism in atrial fibrillation patients.

Authors:  Pamela L Lutsey; Faye L Norby; Neil A Zakai; Richard F MacLehose; Lin Y Chen; Surbhi Shah; Yvonne H Datta; Alvaro Alonso
Journal:  Curr Med Res Opin       Date:  2018-12-03       Impact factor: 2.580

Review 7.  Gastrointestinal Bleeding and Direct Oral Anticoagulants among Patients with Atrial Fibrillation: Risk, Prevention, Management, and Quality of Life.

Authors:  Paolo Zappulla; Valeria Calvi
Journal:  TH Open       Date:  2021-06-16
  7 in total

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