Jeremy Cepek1,2, Uri Lindner1, Sangeet Ghai3, Alyssa S Louis1, Sean R H Davidson4, Mark Gertner5, Eugen Hlasny3, Marshall S Sussman3, Aaron Fenster2,6, John Trachtenberg1. 1. Department of Surgical Oncology, Division of Urology, University Health Network, Toronto, Canada. 2. Robarts Research Institute, The University of Western Ontario, London, Canada. 3. Joint Department of Medical Imaging, University Health Network, Toronto, Canada. 4. Ontario Cancer Institute, University Health Network, Toronto, Canada. 5. Division of Biophysics and Bioimaging, Ontario Cancer Institute, University Health Network, Toronto, Canada. 6. Biomedical Engineering, The University of Western Ontario, London, Canada.
Abstract
BACKGROUND: To present our experiences in initial clinical evaluation of a novel mechatronic system for in-bore guidance of needles to the prostate for MRI-guided prostate interventions in 10 patients. We report accuracy of this device in the context of focal laser ablation therapy for localized prostate cancer. METHODS: An MRI-compatible needle guidance device was developed for transperineal prostate interventions. Ten patients underwent MRI-guided focal laser ablation therapy with device-mediated laser fiber delivery. We recorded needle guidance error and needle delivery time. RESULTS: A total of 37 needle insertions were evaluated. Median needle guidance error was 3.5 mm (interquartile range, 2.1-5.4 mm), and median needle delivery time was 9 min (interquartile range, 6.5-12 min). CONCLUSION: This system provides a reliable method of accurately aligning needle guides for in-bore transperineal needle delivery to the prostate.
BACKGROUND: To present our experiences in initial clinical evaluation of a novel mechatronic system for in-bore guidance of needles to the prostate for MRI-guided prostate interventions in 10 patients. We report accuracy of this device in the context of focal laser ablation therapy for localized prostate cancer. METHODS: An MRI-compatible needle guidance device was developed for transperineal prostate interventions. Ten patients underwent MRI-guided focal laser ablation therapy with device-mediated laser fiber delivery. We recorded needle guidance error and needle delivery time. RESULTS: A total of 37 needle insertions were evaluated. Median needle guidance error was 3.5 mm (interquartile range, 2.1-5.4 mm), and median needle delivery time was 9 min (interquartile range, 6.5-12 min). CONCLUSION: This system provides a reliable method of accurately aligning needle guides for in-bore transperineal needle delivery to the prostate.
Authors: Yue Chen; Sheng Xu; Alexander Squires; Reza Seifabadi; Ismail Baris Turkbey; Peter A Pinto; Peter Choyke; Bradford Wood; Zion Tsz Ho Tse Journal: IEEE Trans Biomed Eng Date: 2017-09-26 Impact factor: 4.538