Katrina S Oyague1, Omar A Mubarak2, Lisa R Nowak2, Jennifer G Gainer2, Thomas F Rehring3, Maureen M O'Brien4, Harris W Hollis5. 1. Department of Graduate Medical Education, General Surgery, Exempla Saint Joseph Hospital, Denver, CO. Electronic address: katrinaoyague@Centura.org. 2. Department of Surgery, Exempla Saint Joseph Hospital, Denver, CO. 3. Department of Vascular Therapy, Colorado Permanente Medical Group, Denver, CO. 4. Department of Biostatistics, University of Colorado, Anschutz Medical Campus, Aurora, CO. 5. Department of Graduate Medical Education, General Surgery, Exempla Saint Joseph Hospital, Denver, CO.
Abstract
BACKGROUND: Open abdominal aortic aneurysm (AAA) repair has gradually been replaced by endovascular aneurysm repair (EVAR). The primary objective of this study is to establish baseline mortality data and compare our institutional mortality rates for ruptured AAA patients with published rates from institutions using similar approaches. METHODS: This study is a retrospective review of 49 patients treated using a structured ruptured AAA (rAAA) protocol in a community teaching hospital. Variables examined include demographics, repair type, device used, presenting systolic blood pressure, presenting glomerular filtration rate, initial hematocrit, transfusions required, and development of postoperative abdominal compartment syndrome. RESULTS: Forty-nine patients were treated using the rAAA protocol and 48 underwent repair. The 30-day mortality for rAAA and symptomatic AAA (sAAA) was 36.4% (12/33) and 20.0% (3/15), respectively, with a mean mortality of 31.2% (15/48). Mortality for rAAA treated by EVAR was 32.0% (8/25). Mortality for rAAA in the open repair group was 33% (2/6). Conversion from EVAR to open procedure (3/48) or 6% resulted in 100% mortality (P = 0.266). The development of abdominal compartment syndrome was an absolute predictor of death as mortality was 100% (P < 0.001). Other significant predictors of death include the following: (1) blood transfusion received during operation required in 10/14 deaths (71%) (P = 0.005) and (2) transfusion received anytime during hospitalization required in 12/14 deaths or 86% (P = 0.017). CONCLUSIONS: The management and endovascular repair of sAAA or rAAA can be improved at the community hospital level by the implementation of standardized protocols. Blood transfusions and development of postoperative abdominal compartment syndrome significantly increase mortality. Individual institutional knowledge of results is critical to effective process improvement and optimal patient outcomes.
BACKGROUND: Open abdominal aortic aneurysm (AAA) repair has gradually been replaced by endovascular aneurysm repair (EVAR). The primary objective of this study is to establish baseline mortality data and compare our institutional mortality rates for ruptured AAA patients with published rates from institutions using similar approaches. METHODS: This study is a retrospective review of 49 patients treated using a structured ruptured AAA (rAAA) protocol in a community teaching hospital. Variables examined include demographics, repair type, device used, presenting systolic blood pressure, presenting glomerular filtration rate, initial hematocrit, transfusions required, and development of postoperative abdominal compartment syndrome. RESULTS: Forty-nine patients were treated using the rAAA protocol and 48 underwent repair. The 30-day mortality for rAAA and symptomatic AAA (sAAA) was 36.4% (12/33) and 20.0% (3/15), respectively, with a mean mortality of 31.2% (15/48). Mortality for rAAA treated by EVAR was 32.0% (8/25). Mortality for rAAA in the open repair group was 33% (2/6). Conversion from EVAR to open procedure (3/48) or 6% resulted in 100% mortality (P = 0.266). The development of abdominal compartment syndrome was an absolute predictor of death as mortality was 100% (P < 0.001). Other significant predictors of death include the following: (1) blood transfusion received during operation required in 10/14 deaths (71%) (P = 0.005) and (2) transfusion received anytime during hospitalization required in 12/14 deaths or 86% (P = 0.017). CONCLUSIONS: The management and endovascular repair of sAAA or rAAA can be improved at the community hospital level by the implementation of standardized protocols. Blood transfusions and development of postoperative abdominal compartment syndrome significantly increase mortality. Individual institutional knowledge of results is critical to effective process improvement and optimal patient outcomes.
Authors: Dan Nicolae Păduraru; Octavian Andronic; Florentina Mușat; Alexandra Bolocan; Mihai Cristian Dumitrașcu; Daniel Ion Journal: Diagnostics (Basel) Date: 2021-12-07