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Literature DB >> 25195010

Kinase inhibitors: an allosteric add-on.

Zachariah H Foda¹, Markus A Seeliger¹.

Abstract

Mesh：

Substances：

Year: 2014 PMID： 25195010 DOI： 10.1038/nchembio.1630

Source DB: PubMed Journal: Nat Chem Biol ISSN： 1552-4450 Impact factor: 15.040

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10 in total

Review 1. The conformational plasticity of protein kinases.

Authors: Morgan Huse; John Kuriyan
Journal: Cell Date: 2002-05-03 Impact factor: 41.582

2. A conserved protonation-dependent switch controls drug binding in the Abl kinase.

Authors: Yibing Shan; Markus A Seeliger; Michael P Eastwood; Filipp Frank; Huafeng Xu; Morten Ø Jensen; Ron O Dror; John Kuriyan; David E Shaw
Journal: Proc Natl Acad Sci U S A Date: 2008-12-24 Impact factor: 11.205

Review 3. Targeting cancer with small molecule kinase inhibitors.

Authors: Jianming Zhang; Priscilla L Yang; Nathanael S Gray
Journal: Nat Rev Cancer Date: 2009-01 Impact factor: 60.716

Review 4. Allostery in disease and in drug discovery.

Authors: Ruth Nussinov; Chung-Jung Tsai
Journal: Cell Date: 2013-04-11 Impact factor: 41.582

5. Cancer statistics, 2007.

Authors: Ahmedin Jemal; Rebecca Siegel; Elizabeth Ward; Taylor Murray; Jiaquan Xu; Michael J Thun
Journal: CA Cancer J Clin Date: 2007 Jan-Feb Impact factor: 508.702

Review 6. Drug-target residence time: critical information for lead optimization.

Authors: Hao Lu; Peter J Tonge
Journal: Curr Opin Chem Biol Date: 2010-07-19 Impact factor: 8.822

7. Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.

Authors: Erick J Morris; Sharda Jha; Clifford R Restaino; Priya Dayananth; Hugh Zhu; Alan Cooper; Donna Carr; Yongi Deng; Weihong Jin; Stuart Black; Brian Long; Jenny Liu; Edward Dinunzio; William Windsor; Rumin Zhang; Shuxia Zhao; Minilik H Angagaw; Elaine M Pinheiro; Jagdish Desai; Li Xiao; Gerald Shipps; Alan Hruza; James Wang; Joe Kelly; Sunil Paliwal; Xiaolei Gao; Boga Sobhana Babu; Liang Zhu; Pierre Daublain; Ling Zhang; Bart A Lutterbach; Marc R Pelletier; Ulrike Philippar; Phieng Siliphaivanh; David Witter; Paul Kirschmeier; W Robert Bishop; Daniel Hicklin; D Gary Gilliland; Lata Jayaraman; Leigh Zawel; Stephen Fawell; Ahmed A Samatar
Journal: Cancer Discov Date: 2013-04-24 Impact factor: 39.397

8. Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.

Authors: Jeffrey F Ohren; Huifen Chen; Alexander Pavlovsky; Christopher Whitehead; Erli Zhang; Peter Kuffa; Chunhong Yan; Patrick McConnell; Cindy Spessard; Craig Banotai; W Thomas Mueller; Amy Delaney; Charles Omer; Judith Sebolt-Leopold; David T Dudley; Iris K Leung; Cathlin Flamme; Joseph Warmus; Michael Kaufman; Stephen Barrett; Haile Tecle; Charles A Hasemann
Journal: Nat Struct Mol Biol Date: 2004-11-14 Impact factor: 15.369

9. The kinetics of binding to p38MAP kinase by analogues of BIRB 796.

Authors: John Regan; Christopher A Pargellis; Pier F Cirillo; Thomas Gilmore; Eugene R Hickey; Gregory W Peet; Alfred Proto; Alan Swinamer; Neil Moss
Journal: Bioorg Med Chem Lett Date: 2003-09-15 Impact factor: 2.823

10. A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics.

Authors: Apirat Chaikuad; Eliana M C Tacconi; Jutta Zimmer; Yanke Liang; Nathanael S Gray; Madalena Tarsounas; Stefan Knapp
Journal: Nat Chem Biol Date: 2014-09-07 Impact factor: 15.040

10 in total

5 in total

1. Delineation of Polypharmacology across the Human Structural Kinome Using a Functional Site Interaction Fingerprint Approach.

Authors: Zheng Zhao; Li Xie; Lei Xie; Philip E Bourne
Journal: J Med Chem Date: 2016-03-17 Impact factor: 7.446