Literature DB >> 25187360

Dexmedetomidine for infant pulmonary function testing.

Patrick Callahan1, Swaroop J Pinto, Geoffrey Kurland, James G Cain, Etsuro K Motoyama, Daniel J Weiner.   

Abstract

For the last thirty years, oral chloral hydrate has been used for sedation of infants for lung function testing. Recently, however, availability of chloral hydrate became severely limited in the United States after two manufacturers discontinued manufacturing in 2012. Due to these limitations and the recent and ongoing shortage of chloral hydrate, other medications have been proposed for lung function testing, including midazolam and propofol. Herein, we describe our limited experience using intravenous dexmedetomedine (DMED), a medication thus far described as having minimal effect on pulmonary function or respiratory drive.
© 2014 Wiley Periodicals, Inc.

Entities:  

Keywords:  infant pulmonary function; pulmonary function testing (PFT)

Mesh:

Substances:

Year:  2014        PMID: 25187360     DOI: 10.1002/ppul.23100

Source DB:  PubMed          Journal:  Pediatr Pulmonol        ISSN: 1099-0496


  3 in total

1.  Effects of dexmedetomidine on oxidative stress and inflammatory response in lungs during mechanical ventilation in COPD rats.

Authors:  Pengcheng Li; Jing Han; Dan Zhang; Shu Cao; Chunyu Su
Journal:  Exp Ther Med       Date:  2019-12-17       Impact factor: 2.447

Review 2.  Going the Extra Mile: Why Clinical Research in Cystic Fibrosis Must Include Children.

Authors:  Rebecca Dobra; Siân Bentley; Claire Edmondson; Maxine Ovens; Clare Saunders; Christopher Short; Gemma Wilson; Jane C Davies; Andrew Bush
Journal:  Children (Basel)       Date:  2022-07-20

3.  Efficacy and safety of chloral hydrate sedation in infants for pulmonary function tests.

Authors:  Gustavo Falbo Wandalsen; Fernanda de Cordoba Lanza; Márcia Cristina Pires Nogueira; Dirceu Solé
Journal:  Rev Paul Pediatr       Date:  2016-06-22
  3 in total

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