OBJECTIVE: To examine the relationship between clinical characteristics and cognitive performance in service members and veterans with histories of blast-related mild traumatic brain injury (mTBI). DESIGN: This study consisted of 40 Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) service members and veterans; 20 participants reported blast exposure and alteration of mental status consistent with mTBI and 20 participants denied blast exposure and had no history of traumatic brain injury (TBI), but could have experienced extra-cranial injuries. Measures of simple reaction time, processing speed, visual attention, working memory and mathematical processing were used to assess long-term effects of mTBI. Measures of post-traumatic stress symptom severity, pain intensity, sleep difficulty and subjective appraisal of cognition at time of testing were also obtained. Multivariate analyses were conducted with clinical characteristics and mTBI history as predictors of cognitive performance. RESULTS: There was no evidence of an effect of mTBI history on cognitive performance in this sample. However, post-traumatic stress symptom severity was significantly related to two measures of cognitive performance. CONCLUSIONS: This study demonstrated the importance of considering the effects of current clinical symptoms (e.g. post-traumatic stress) as possibly having greater influence on current cognitive functioning than the effects of a remote history of mTBI.
OBJECTIVE: To examine the relationship between clinical characteristics and cognitive performance in service members and veterans with histories of blast-related mild traumatic brain injury (mTBI). DESIGN: This study consisted of 40 Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) service members and veterans; 20 participants reported blast exposure and alteration of mental status consistent with mTBI and 20 participants denied blast exposure and had no history of traumatic brain injury (TBI), but could have experienced extra-cranial injuries. Measures of simple reaction time, processing speed, visual attention, working memory and mathematical processing were used to assess long-term effects of mTBI. Measures of post-traumatic stress symptom severity, pain intensity, sleep difficulty and subjective appraisal of cognition at time of testing were also obtained. Multivariate analyses were conducted with clinical characteristics and mTBI history as predictors of cognitive performance. RESULTS: There was no evidence of an effect of mTBI history on cognitive performance in this sample. However, post-traumatic stress symptom severity was significantly related to two measures of cognitive performance. CONCLUSIONS: This study demonstrated the importance of considering the effects of current clinical symptoms (e.g. post-traumatic stress) as possibly having greater influence on current cognitive functioning than the effects of a remote history of mTBI.
Authors: Jennifer J Vasterling; Mihaela Aslan; Lewina O Lee; Susan P Proctor; John Ko; Shawna Jacob; John Concato Journal: J Int Neuropsychol Soc Date: 2017-12-04 Impact factor: 2.892
Authors: Srinivasu Kallakuri; Alok Desai; Ke Feng; Sharvani Tummala; Tal Saif; Chaoyang Chen; Liying Zhang; John M Cavanaugh; Albert I King Journal: PLoS One Date: 2017-01-20 Impact factor: 3.240
Authors: Richard J Servatius; Justin D Handy; Michael J Doria; Catherine E Myers; Christine E Marx; Robert Lipsky; Nora Ko; Pelin Avcu; W Geoffrey Wright; Jack W Tsao Journal: Front Psychol Date: 2017-09-14
Authors: Kristin W Samuelson; Krista Engle; Linda Abadjian; Joshua Jordan; Alisa Bartel; Margaret Talbot; Tyler Powers; Lori Bryan; Charles Benight Journal: Front Neurol Date: 2020-11-26 Impact factor: 4.003
Authors: Matthew J Muelbl; Megan L Slaker; Alok S Shah; Natalie N Nawarawong; Clayton H Gerndt; Matthew D Budde; Brian D Stemper; Christopher M Olsen Journal: Sci Rep Date: 2018-07-02 Impact factor: 4.379