Literature DB >> 25179500

Prostate cancer: TMPRSS2 promotes metastasis through proteolysis.

Robert Phillips.   

Abstract

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Year:  2014        PMID： 25179500     DOI： 10.1038/nrurol.2014.238

Source DB:  PubMed          Journal:  Nat Rev Urol        ISSN： 1759-4812            Impact factor:   14.432


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  1 in total

1.  The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.

Authors:  Jared M Lucas; Cynthia Heinlein; Tom Kim; Susana A Hernandez; Muzdah S Malik; Lawrence D True; Colm Morrissey; Eva Corey; Bruce Montgomery; Elahe Mostaghel; Nigel Clegg; Ilsa Coleman; Christopher M Brown; Eric L Schneider; Charles Craik; Julian A Simon; Antonio Bedalov; Peter S Nelson
Journal:  Cancer Discov       Date:  2014-08-13       Impact factor: 39.397
  1 in total

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