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Literature DB >> 25179381

Pulmonary hypertensive crisis following ethanol sclerotherapy for a complex vascular malformation.

G Cordero-Schmidt¹, M B Wallenstein², M Ozen², N A Shah², E Jackson³, D M Hovsepian⁴, J P Palma².

Abstract

Anhydrous ethanol is a commonly used sclerotic agent for treating vascular malformations. We describe the case of a full-term 15-day-old female with a complex venolymphatic malformation involving the face and orbit. During treatment of the lesion with ethanol sclerotherapy, she suffered acute pulmonary hypertensive crisis. We discuss the pathophysiology of pulmonary hypertension related to ethanol sclerotherapy, and propose that hemolysis plays a significant role. Recommendations for evaluation, monitoring and management of this complication are also discussed.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Ethanol

Year: 2014 PMID： 25179381 PMCID： PMC4845903 DOI： 10.1038/jp.2014.88

Source DB: PubMed Journal: J Perinatol ISSN： 0743-8346 Impact factor: 2.521

16 in total

1. Ethanol-induced acute pulmonary hypertension and right ventricular dysfunction in pigs.

Authors: A Sidi; B Naik; J D Muehlschlegel; D S Kirby; E B Lobato
Journal: Br J Anaesth Date: 2008-04 Impact factor: 9.166

2. Prediction of the effect of injected ethanol on pulmonary arterial pressure during sclerotherapy of arteriovenous malformations: relationship with dose of ethanol.

Authors: Justin S Ko; Jie A Kim; Young S Do; Min A Kwon; Soo J Choi; Mi S Gwak; Jeong J Lee; Mikyung Yang
Journal: J Vasc Interv Radiol Date: 2008-11-22 Impact factor: 3.464

Review 3. The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease.

Authors: Russell P Rother; Leonard Bell; Peter Hillmen; Mark T Gladwin
Journal: JAMA Date: 2005-04-06 Impact factor: 56.272

Pulmonary hypertensive crisis following ethanol sclerotherapy for a complex vascular malformation.

1. Ethanol-induced acute pulmonary hypertension and right ventricular dysfunction in pigs.

2. Prediction of the effect of injected ethanol on pulmonary arterial pressure during sclerotherapy of arteriovenous malformations: relationship with dose of ethanol.

Review 3. The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease.

4. Fatal cardiovascular collapse during ethanol sclerotherapy of a venous malformation.

5. Asystole during percutaneous ethanol injection of symptomatic vertebral haemangioma.

6. Multistage ethanol sclerotherapy of soft-tissue arteriovenous malformations: effect on pulmonary arterial pressure.

7. Ethanol sclerotherapy of venous malformations: evaluation of systemic ethanol contamination.

8. Ethyl alcohol ingestion in children. A 15-year review.

9. Cardiovascular collapse during ethanol sclerotherapy in a pediatric patient.

10. Mechanism of hemolysis of red blood cell mediated by ethanol.

1. Marsupialization and sclerotherapy with povidone iodine and ethanol of a branchial remnant cyst in an Arabian filly.