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Literature DB >> 25178894

Gd-encapsulated carbonaceous dots with efficient renal clearance for magnetic resonance imaging.

Hongmin Chen¹, Geoffrey D Wang², Wei Tang², Trever Todd², Zipeng Zhen², Chu Tsang², Khan Hekmatyar³, Taku Cowger², Richard Hubbard², Weizhong Zhang², John Stickney², Baozhong Shen⁴, Jin Xie⁵.

Abstract

Nanoprobes for MRI and optical imaging are demonstrated. Gd@C-dots possess strong fluorescence and can effectively enhance signals on T1 -weighted MR images. The nanoprobes have low toxicity, and, despite a relatively large size, can be efficiently excreted by renal clearance from the host after systemic injection.

Entities: CellLine Chemical Disease Gene Species

Keywords: MRI; T1 contrast agent; carbonaceous dots; gadolinium; renal clearance

Mesh：

Substances：

Year: 2014 PMID： 25178894 PMCID： PMC4885638 DOI： 10.1002/adma.201402964

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

31 in total

1. Hydrothermal treatment of grass: a low-cost, green route to nitrogen-doped, carbon-rich, photoluminescent polymer nanodots as an effective fluorescent sensing platform for label-free detection of Cu(II) ions.

Authors: Sen Liu; Jingqi Tian; Lei Wang; Yingwei Zhang; Xiaoyun Qin; Yonglan Luo; Abdullah M Asiri; Abdulrahman O Al-Youbi; Xuping Sun
Journal: Adv Mater Date: 2012-03-15 Impact factor: 30.849

2. Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes.

Authors: D Liu; A Mori; L Huang
Journal: Biochim Biophys Acta Date: 1992-02-17

3. Surface functionalized carbogenic quantum dots.

Authors: Athanasios B Bourlinos; Andreas Stassinopoulos; Demetrios Anglos; Radek Zboril; Michael Karakassides; Emmanuel P Giannelis
Journal: Small Date: 2008-04 Impact factor: 13.281

4. A synergistically enhanced T(1) -T(2) dual-modal contrast agent.

Authors: Zijian Zhou; Dengtong Huang; Jianfeng Bao; Qiaoli Chen; Gang Liu; Zhong Chen; Xiaoyuan Chen; Jinhao Gao
Journal: Adv Mater Date: 2012-09-13 Impact factor: 30.849

Review 5. Nanoparticle PEGylation for imaging and therapy.

Authors: Jesse V Jokerst; Tatsiana Lobovkina; Richard N Zare; Sanjiv S Gambhir
Journal: Nanomedicine (Lond) Date: 2011-06 Impact factor: 5.307

Review 6. Gadolinium-induced nephrogenic systemic fibrosis.

Authors: Richard N Hellman
Journal: Semin Nephrol Date: 2011-05 Impact factor: 5.299

7. Structure-activity relationship of macrocyclic and linear gadolinium chelates: investigation of transmetallation effect on the zinc-dependent metallopeptidase angiotensin-converting enzyme.

Authors: C Corot; J M Idee; A M Hentsch; R Santus; C Mallet; V Goulas; B Bonnemain; D Meyer
Journal: J Magn Reson Imaging Date: 1998 May-Jun Impact factor: 4.813

8. Biodegradable polysilsesquioxane nanoparticles as efficient contrast agents for magnetic resonance imaging.

Authors: Juan L Vivero-Escoto; William J Rieter; Honam Lau; Rachel C Huxford-Phillips; Wenbin Lin
Journal: Small Date: 2013-04-24 Impact factor: 13.281

Review 9. Gadolinium-contrast toxicity in patients with kidney disease: nephrotoxicity and nephrogenic systemic fibrosis.

Authors: Mark A Perazella
Journal: Curr Drug Saf Date: 2008-01

10. Hybrid gadolinium oxide nanoparticles: multimodal contrast agents for in vivo imaging.

Authors: Jean-Luc Bridot; Anne-Charlotte Faure; Sophie Laurent; Charlotte Rivière; Claire Billotey; Bassem Hiba; Marc Janier; Véronique Josserand; Jean-Luc Coll; Luce Vander Elst; Robert Muller; Stéphane Roux; Pascal Perriat; Olivier Tillement
Journal: J Am Chem Soc Date: 2007-03-31 Impact factor: 15.419

29 in total

1. Iron oxide decorated MoS2 nanosheets with double PEGylation for chelator-free radiolabeling and multimodal imaging guided photothermal therapy.

Authors: Teng Liu; Sixiang Shi; Chao Liang; Sida Shen; Liang Cheng; Chao Wang; Xuejiao Song; Shreya Goel; Todd E Barnhart; Weibo Cai; Zhuang Liu
Journal: ACS Nano Date: 2015-01-08 Impact factor: 15.881

Gd-encapsulated carbonaceous dots with efficient renal clearance for magnetic resonance imaging.

1. Hydrothermal treatment of grass: a low-cost, green route to nitrogen-doped, carbon-rich, photoluminescent polymer nanodots as an effective fluorescent sensing platform for label-free detection of Cu(II) ions.

2. Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes.

3. Surface functionalized carbogenic quantum dots.

4. A synergistically enhanced T(1) -T(2) dual-modal contrast agent.

Review 5. Nanoparticle PEGylation for imaging and therapy.

Review 6. Gadolinium-induced nephrogenic systemic fibrosis.

7. Structure-activity relationship of macrocyclic and linear gadolinium chelates: investigation of transmetallation effect on the zinc-dependent metallopeptidase angiotensin-converting enzyme.

8. Biodegradable polysilsesquioxane nanoparticles as efficient contrast agents for magnetic resonance imaging.

Review 9. Gadolinium-contrast toxicity in patients with kidney disease: nephrotoxicity and nephrogenic systemic fibrosis.

10. Hybrid gadolinium oxide nanoparticles: multimodal contrast agents for in vivo imaging.

1. Iron oxide decorated MoS2 nanosheets with double PEGylation for chelator-free radiolabeling and multimodal imaging guided photothermal therapy.

Review 2. Renal clearable noble metal nanoparticles: photoluminescence, elimination, and biomedical applications.

3. High-contrast Noninvasive Imaging of Kidney Clearance Kinetics Enabled by Renal Clearable Nanofluorophores.

4. A porphyrin-PEG polymer with rapid renal clearance.

Review 5. Nanomedicines for renal disease: current status and future applications.

Review 6. Clearance Pathways and Tumor Targeting of Imaging Nanoparticles.

7. Tailoring Renal Clearance and Tumor Targeting of Ultrasmall Metal Nanoparticles with Particle Density.

Review 8. Serum protein adsorption and excretion pathways of metal nanoparticles.

9. Gadolinium-Encapsulated Graphene Carbon Nanotheranostics for Imaging-Guided Photodynamic Therapy.

10. In Vivo X-ray Imaging of Transport of Renal Clearable Gold Nanoparticles in the Kidneys.