Sophie J Barkl1, Suncica Lah2, Anthony W F Harris3, Leanne M Williams4. 1. School of Psychology, University of Sydney, Sydney, NSW, Australia; The Brain Dynamics Centre, Sydney Medical School and Westmead Millennium Institute, University of Sydney, Sydney, NSW, Australia; ARC Centre of Excellence in Cognition and its Disorders, Sydney, NSW, Australia. 2. School of Psychology, University of Sydney, Sydney, NSW, Australia; ARC Centre of Excellence in Cognition and its Disorders, Sydney, NSW, Australia. 3. The Brain Dynamics Centre, Sydney Medical School and Westmead Millennium Institute, University of Sydney, Sydney, NSW, Australia; Discipline of Psychiatry, Sydney Medical School, University of Sydney, Sydney, NSW, Australia. 4. The Brain Dynamics Centre, Sydney Medical School and Westmead Millennium Institute, University of Sydney, Sydney, NSW, Australia; Discipline of Psychiatry, Sydney Medical School, University of Sydney, Sydney, NSW, Australia; Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA. Electronic address: leawilliams@stanford.edu.
Abstract
OBJECTIVE: Patients with chronic schizophrenia are characterized by deficits in identifying facial expressions of emotion, and these deficits relate to impaired social and occupational function. It is not yet known if these deficits are trait-like and present at the onset of psychosis, preceding a subsequent diagnosis of schizophrenia. Our objective was to systematically review and analyze the extant literature to assess if there is a consistent profile of emotion identification problems in early-onset and first-episode psychosis. METHODS: We conducted a systematic review and meta-analysis of 12 peer-reviewed studies of facial emotion identification in early-onset and first-episode psychosis, published between 1980 and March 2013. We examined the average mean difference between patients and controls on measures of facial emotion identification. RESULTS: Findings suggest that patients with early-onset and first-episode psychosis have impairment in identifying facial expressions of biologically salient emotion. Across the 12 studies, the onset of psychosis was distinguished by a generalized effect of significantly poorer accuracy for identifying facial expressions of emotion than healthy controls, and this difference had a substantial effect size (d=-0.88, N=378, 95% CI=-1.42 to -0.32). Within this general effect some emotions were also harder for patients to identify than others, with the magnitude of impairment found to be (i) large for disgust, fear and surprise, and (ii) medium for sadness, and happiness. No between groups mean differences were found for anger or neutral facial expressions. CONCLUSIONS: Deficits in facial emotion identification are evident at first onset of a psychotic episode. The findings suggest that, over and above a generalized deficit in identifying facial emotion, patients may find some emotions harder to identifying than others. This reflects findings with chronic schizophrenia populations and suggests that emotion identification impairment represents a trait susceptibility marker, rather than a sequeale of illness. They signal the urgent need to treat emotion identification deficits at the onset of illness, which could improve functional outcomes.
OBJECTIVE:Patients with chronic schizophrenia are characterized by deficits in identifying facial expressions of emotion, and these deficits relate to impaired social and occupational function. It is not yet known if these deficits are trait-like and present at the onset of psychosis, preceding a subsequent diagnosis of schizophrenia. Our objective was to systematically review and analyze the extant literature to assess if there is a consistent profile of emotion identification problems in early-onset and first-episode psychosis. METHODS: We conducted a systematic review and meta-analysis of 12 peer-reviewed studies of facial emotion identification in early-onset and first-episode psychosis, published between 1980 and March 2013. We examined the average mean difference between patients and controls on measures of facial emotion identification. RESULTS: Findings suggest that patients with early-onset and first-episode psychosis have impairment in identifying facial expressions of biologically salient emotion. Across the 12 studies, the onset of psychosis was distinguished by a generalized effect of significantly poorer accuracy for identifying facial expressions of emotion than healthy controls, and this difference had a substantial effect size (d=-0.88, N=378, 95% CI=-1.42 to -0.32). Within this general effect some emotions were also harder for patients to identify than others, with the magnitude of impairment found to be (i) large for disgust, fear and surprise, and (ii) medium for sadness, and happiness. No between groups mean differences were found for anger or neutral facial expressions. CONCLUSIONS: Deficits in facial emotion identification are evident at first onset of a psychotic episode. The findings suggest that, over and above a generalized deficit in identifying facial emotion, patients may find some emotions harder to identifying than others. This reflects findings with chronic schizophrenia populations and suggests that emotion identification impairment represents a trait susceptibility marker, rather than a sequeale of illness. They signal the urgent need to treat emotion identification deficits at the onset of illness, which could improve functional outcomes.
Authors: Yi Wang; Zhi Li; Wen-Hua Liu; Xin-Hua Wei; Xin-Qing Jiang; Simon S Y Lui; Suzanne Ho-Wai So; Eric F C Cheung; Martin Debbane; Raymond C K Chan Journal: Schizophr Bull Date: 2018-10-15 Impact factor: 9.306
Authors: Nora I Muros; Arturo S García; Cristina Forner; Pablo López-Arcas; Guillermo Lahera; Roberto Rodriguez-Jimenez; Karen N Nieto; José Miguel Latorre; Antonio Fernández-Caballero; Patricia Fernández-Sotos Journal: J Clin Med Date: 2021-04-28 Impact factor: 4.241
Authors: Ana Catalan; Maider Gonzalez de Artaza; Sonia Bustamante; Pablo Orgaz; Luis Osa; Virxinia Angosto; Cristina Valverde; Amaia Bilbao; Arantza Madrazo; Jim van Os; Miguel Angel Gonzalez-Torres Journal: PLoS One Date: 2016-07-28 Impact factor: 3.240