Literature DB >> 25177571

Emergency Diagnosis of Giant Cell Tumour (GCT) of Spine by Image Guided Fine Needle Aspiration Cytology (FNAC).

Prem Singh1, Manish Chaudhry1, Amitoj Singh2.   

Abstract

Giant cell tumour (GCT) of spine is an extremely rare neoplasm accounting 0.5% to 1.5% of all cases. The patient usually presents with weakness of lower limbs. We describe a case of 25-year-old male who presented with sudden onset of paraplegia. On plain radiograph there was an osteolytic lesion in T9 vertebra. Computed tomography (CT) scan revealed expansile lytic lesion in T9 vertebral body with involvement of posterior elements on right side with associated soft tissue mass in the extradural location extending into the spinal cord. Further Magnetic Resonance Imaging (MRI) scan (T1 contrast) showed the enhancing extradural mass involving spinal cord from D 8-10 levels. A provisional radiological diagnosis of GCT was made. A CT guided FNAC of the mass was performed which revealed typical cytological features of Giant cell tumour. Role of image guided Fine Needle Aspiration Cytology (FNAC) of vertebral mass and its role in emergency situations with clear emphasis on differential diagnosis is highlighted.

Entities:  

Keywords:  Giant cell tumour; Paraplegia; Stromal cells; Vertebral mass

Year:  2014        PMID: 25177571      PMCID: PMC4149077          DOI: 10.7860/JCDR/2014/8845.4564

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  3 in total

1.  Chondroblastoma of bone: use of fine-needle aspiration biopsy and potential diagnostic pitfalls.

Authors:  S E Kilpatrick; E J Pike; K R Geisinger; W G Ward
Journal:  Diagn Cytopathol       Date:  1997-01       Impact factor: 1.582

2.  Giant-cell tumors of the cervical spine: case report.

Authors:  Christopher L Hunter; Donato Pacione; Mark Hornyak; Raj Murali
Journal:  Neurosurgery       Date:  2006-11       Impact factor: 4.654

Review 3.  Giant cell tumor of the thoracic spine: case report and review of the literature.

Authors:  Daniel Refai; Gavin P Dunn; Paul Santiago
Journal:  Surg Neurol       Date:  2008-01-22
  3 in total
  2 in total

1.  Giant-cell tumor of the rib cage extending to the spine : Case report.

Authors:  Juan Francisco Blanco; Marcelo Jiménez; Diego Rendón; David Pescador; Jorge Hugo Villafañe; Diego Garbossa; Pedro Berjano
Journal:  Orthopade       Date:  2018-05       Impact factor: 1.087

2.  Imaging Features of Aggressive Giant Cell Tumors of the Mobile Spine: Retrospective Analysis of 101 Patients From Single Center.

Authors:  Bei Yuan; Lihua Zhang; Shaomin Yang; Hanqiang Ouyang; Songbo Han; Liang Jiang; Feng Wei; Huishu Yuan; Xiaoguang Liu; Zhongjun Liu
Journal:  Global Spine J       Date:  2021-01-27
  2 in total

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