Literature DB >> 25177079

Dynamic Mode Decomposition of Fontan Hemodynamics in an Idealized Total Cavopulmonary Connection.

Yann T Delorme1, Anna-Elodie M Kerlo1, Kameswararao Anupindi1, Mark D Rodefeld2, Steven H Frankel1.   

Abstract

Univentricular heart disease is the leading cause of death from any birth defect in the first year of life. Typically, patients have to undergo three open heart surgical procedures within the first few years of their lives to eventually directly connect the superior and inferior vena cavae to the left and right pulmonary arteries forming the Total Cavopulmonary Connection or TCPC. The end result is a weak circulation where the single working ventricle pumps oxygenated blood to the body and de-oxygenated blood flows passively through the TCPC into the lungs. The fluid dynamics of the TCPC junction involve confined impinging jets resulting in a highly unstable flow, significant mechanical energy dissipation, and undesirable pressure loss. Understanding and predicting such flows is important for improving the surgical procedure and for the design of mechanical cavopulmonary assist devices. In this study, Dynamic Mode Decomposition (DMD) is used to analyze previously obtained Stereoscopic Particle Imaging Velocimetry (SPIV) data and Large Eddy Simulation (LES) results for an idealized TCPC. Analysis of the DMD modes from the SPIV and LES serve to both highlight the unsteady vortical dynamics and the qualitative agreement between measurements and simulations.

Entities:  

Keywords:  Dynamic Mode Decomposition; Flow instabilities; Fontan circulation

Year:  2014        PMID: 25177079      PMCID: PMC4146495          DOI: 10.1088/0169-5983/46/4/041425

Source DB:  PubMed          Journal:  Fluid Dyn Res        ISSN: 0169-5983            Impact factor:   1.067


  12 in total

1.  Optimization of inflow waveform phase-difference for minimized total cavopulmonary power loss.

Authors:  Onur Dur; Curt G DeGroff; Bradley B Keller; Kerem Pekkan
Journal:  J Biomech Eng       Date:  2010-03       Impact factor: 2.097

2.  Surgical results of patients with a functional single ventricle.

Authors:  Jeong Ryul Lee; Jae Sung Choi; Chang Hyun Kang; Eun Jung Bae; Yong Jin Kim; Joon Ryang Rho
Journal:  Eur J Cardiothorac Surg       Date:  2003-11       Impact factor: 4.191

3.  Computational fluid dynamics simulations in realistic 3-D geometries of the total cavopulmonary anastomosis: the influence of the inferior caval anastomosis.

Authors:  Francesco Migliavacca; Gabriele Dubini; Edward L Bove; Marc R de Leval
Journal:  J Biomech Eng       Date:  2003-12       Impact factor: 2.097

Review 4.  The Fontan circulation.

Authors:  Marc Gewillig
Journal:  Heart       Date:  2005-06       Impact factor: 5.994

5.  Introduction of a new optimized total cavopulmonary connection.

Authors:  Dennis D Soerensen; Kerem Pekkan; Diane de Zélicourt; Shiva Sharma; Kirk Kanter; Mark Fogel; Ajit P Yoganathan
Journal:  Ann Thorac Surg       Date:  2007-06       Impact factor: 4.330

6.  Evaluation of a novel Y-shaped extracardiac Fontan baffle using computational fluid dynamics.

Authors:  Alison L Marsden; Adam J Bernstein; V Mohan Reddy; Shawn C Shadden; Ryan L Spilker; Frandics P Chan; Charles A Taylor; Jeffrey A Feinstein
Journal:  J Thorac Cardiovasc Surg       Date:  2009-02       Impact factor: 5.209

7.  A novel multiblock immersed boundary method for large eddy simulation of complex arterial hemodynamics.

Authors:  Kameswararao Anupindi; Yann Delorme; Dinesh A Shetty; Steven H Frankel
Journal:  J Comput Phys       Date:  2013-12-01       Impact factor: 3.553

8.  Surgical repair of tricuspid atresia.

Authors:  F Fontan; E Baudet
Journal:  Thorax       Date:  1971-05       Impact factor: 9.139

9.  Hypoplastic left heart syndrome: experience with palliative surgery.

Authors:  W I Norwood; J K Kirklin; S P Sanders
Journal:  Am J Cardiol       Date:  1980-01       Impact factor: 2.778

10.  Cardiac transplantation after the Fontan or Glenn procedure.

Authors:  K Anitha Jayakumar; Linda J Addonizio; Maryanne R Kichuk-Chrisant; Mark E Galantowicz; Jacqueline M Lamour; Jan M Quaegebeur; Daphne T Hsu
Journal:  J Am Coll Cardiol       Date:  2004-11-16       Impact factor: 24.094

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.