Literature DB >> 25176032

Sparing surgery with the use of TiNi-based endografts in larynx cancer patients.

Marat Muhamedov1, Denis Kulbakin, Victor Gunther, Evgeniy Choynzonov, Timofey Chekalkin, Valentina Hodorenko.   

Abstract

BACKGROUND AND OBJECTIVES: Purpose of this study was to improve a technique of sparing surgery in patients with laryngeal cancer by using TiNi-based endografts and to achieve well functional and oncological results after laryngectomy.
METHODS: Totally 120 patients with laryngeal cancer were observed (T2-3 N0-1 M0 ). We have developed a method of laryngeal reconstruction using TiNi-based endografts. All endografts show the superelastic behavior recovering the shape. All patients have undergone different types of sparing surgeries with simultaneous replacement with endografts.
RESULTS: Voice function was completely saved in 112 cases and partially in 8 ones. Respiratory function was fully restored in 106 patients. The protective function of the larynx was achieved in 116 patients.
CONCLUSION: The technique allowed to achieve well oncological (the 5-year and overall recurrence-free survival rates of all 120 patients were 83% and 76%, respectively) and functional (larynx function was saved in 93% of cases) outcomes after extensive and subtotal resections in patients with locally distributed larynx cancer.
© 2014 Wiley Periodicals, Inc.

Entities:  

Keywords:  TiNi-based endograft; larynx cancer; larynx reconstruction; prefabricated flap; sparing surgery

Mesh:

Substances:

Year:  2014        PMID: 25176032     DOI: 10.1002/jso.23779

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  2 in total

1.  Sparing Surgery for the Successful Treatment of Thyroid Papillary Carcinoma Invading the Trachea: A Case Report.

Authors:  Denis Kulbakin; Timofey Chekalkin; Marat Muhamedov; Evgeniy Choynzonov; Ji-Hoon Kang; Seung-Baik Kang; Victor Gunther
Journal:  Case Rep Oncol       Date:  2016-11-18

2.  Repair of Orbital Post-Traumatic Wall Defects by Custom-Made TiNi Mesh Endografts.

Authors:  Valentin Shtin; Valeriy Novikov; Timofey Chekalkin; Victor Gunther; Ekaterina Marchenko; Evgeniy Choynzonov; Seung Baik Kang; Moon Jong Chang; Ji Hoon Kang; Aleksei Obrosov
Journal:  J Funct Biomater       Date:  2019-06-27
  2 in total

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