Literature DB >> 25175302

Intervening in ageing to prevent the diseases of ageing.

Linda Partridge1.   

Abstract

Increases in human lifespan worldwide have revealed that advancing age is the predominant risk factor for major life-threatening diseases. Recent work has shown that ageing in diverse animals, including humans, is malleable to specific types of genetic mutation, diet, and drugs that can extend lifespan and improve health during ageing. These findings point to the prospect of broad-spectrum preventive medicine for the diseases of ageing based on intervention in relevant aspects of the ageing process itself.
Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  ageing; ageing-related disease; insulin/insulin-like growth factor and TOR signalling

Mesh:

Year:  2014        PMID: 25175302     DOI: 10.1016/j.tem.2014.08.003

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN: 1043-2760            Impact factor:   12.015


  21 in total

Review 1.  Nutritional strategies to optimise cognitive function in the aging brain.

Authors:  Devin Wahl; Victoria C Cogger; Samantha M Solon-Biet; Rosilene V R Waern; Rahul Gokarn; Tamara Pulpitel; Rafael de Cabo; Mark P Mattson; David Raubenheimer; Stephen J Simpson; David G Le Couteur
Journal:  Ageing Res Rev       Date:  2016-06-26       Impact factor: 10.895

2.  In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.

Authors:  Alejandro Ocampo; Pradeep Reddy; Paloma Martinez-Redondo; Aida Platero-Luengo; Fumiyuki Hatanaka; Tomoaki Hishida; Mo Li; David Lam; Masakazu Kurita; Ergin Beyret; Toshikazu Araoka; Eric Vazquez-Ferrer; David Donoso; Jose Luis Roman; Jinna Xu; Concepcion Rodriguez Esteban; Gabriel Nuñez; Estrella Nuñez Delicado; Josep M Campistol; Isabel Guillen; Pedro Guillen; Juan Carlos Izpisua Belmonte
Journal:  Cell       Date:  2016-12-15       Impact factor: 41.582

3.  Early sirtuin 2 inhibition prevents age-related cognitive decline in a senescence-accelerated mouse model.

Authors:  Teresa Diaz-Perdigon; Francisco B Belloch; Ana Ricobaraza; Elghareeb E Elboray; Takayoshi Suzuki; Rosa M Tordera; Elena Puerta
Journal:  Neuropsychopharmacology       Date:  2019-08-30       Impact factor: 7.853

Review 4.  Macronutrients and caloric intake in health and longevity.

Authors:  Samantha M Solon-Biet; Sarah J Mitchell; Rafael de Cabo; David Raubenheimer; David G Le Couteur; Stephen J Simpson
Journal:  J Endocrinol       Date:  2015-05-28       Impact factor: 4.286

5.  Maximum reproductive lifespan correlates with CD33rSIGLEC gene number: Implications for NADPH oxidase-derived reactive oxygen species in aging.

Authors:  Naazneen Khan; Stuart K Kim; Pascal Gagneux; Laura L Dugan; Ajit Varki
Journal:  FASEB J       Date:  2019-12-24       Impact factor: 5.191

6.  Anxiety and task performance changes in an aging mouse model.

Authors:  Erika D Nolte; Keith A Nolte; Shirley ShiDu Yan
Journal:  Biochem Biophys Res Commun       Date:  2019-04-24       Impact factor: 3.575

7.  Redistribution of Histone Marks on Inflammatory Genes Associated With Intracerebral Hemorrhage-Induced Acute Brain Injury in Aging Rats.

Authors:  Qin Zhang; Wei-Lin Kong; Jun-Jie Yuan; Qiong Chen; Chang-Xiong Gong; Liang Liu; Fa-Xiang Wang; Jia-Cheng Huang; Guo-Qiang Yang; Kai Zhou; Rui Xu; Xiao-Yi Xiong; Qing-Wu Yang
Journal:  Front Neurosci       Date:  2022-04-15       Impact factor: 4.677

8.  Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes.

Authors:  Vicky Lutchman; Younes Medkour; Eugenie Samson; Anthony Arlia-Ciommo; Pamela Dakik; Berly Cortes; Rachel Feldman; Sadaf Mohtashami; Mélissa McAuley; Marisa Chancharoen; Belise Rukundo; Éric Simard; Vladimir I Titorenko
Journal:  Oncotarget       Date:  2016-03-29

9.  Drug-induced premature senescence model in human dental follicle stem cells.

Authors:  Yuanfen Zhai; Rongbin Wei; Junjun Liu; Huihui Wang; Wenping Cai; Mengmeng Zhao; Yongguang Hu; Shuwei Wang; Tianshu Yang; Xiaodong Liu; Jianhua Yang; Shangfeng Liu
Journal:  Oncotarget       Date:  2017-01-31

Review 10.  A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis.

Authors:  Anthony Arlia-Ciommo; Veronika Svistkova; Sadaf Mohtashami; Vladimir I Titorenko
Journal:  Oncotarget       Date:  2016-02-02
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