Literature DB >> 25174720

Chemical modification of temoporfin--a second generation photosensitizer activated using upconverting nanoparticles for singlet oxygen generation.

Q Yu1, E M Rodriguez, R Naccache, P Forgione, G Lamoureux, F Sanz-Rodriguez, D Scheglmann, J A Capobianco.   

Abstract

LiYF4:Tm(3+)/Yb(3+) upconverting nanoparticles (UCNPs) were functionalized with the second generation photosensitizer 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (m-THPC, Temoporfin, Foscan®). m-THPC was modified using 4-(bromomethyl)benzoic acid, which induced a bathochromic shift of the m-THPC blue absorption peak. The nanoconstruct causes up to 70% cell death under 980 nm irradiation.

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Year:  2014        PMID: 25174720     DOI: 10.1039/c4cc05867d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  5 in total

1.  Milk-exosome based pH/light sensitive drug system to enhance anticancer activity against oral squamous cell carcinoma.

Authors:  Qian Zhang; Qi Xiao; Honglin Yin; Chengwan Xia; Yumei Pu; Zhifeng He; Qingang Hu; Jianquan Wang; Yuxin Wang
Journal:  RSC Adv       Date:  2020-07-29       Impact factor: 3.361

2.  Luminescence dynamics and enhancement of the UV and visible emissions of Tm3+ in LiYF4:Yb3+,Tm3+ upconverting nanoparticles.

Authors:  Steven L Maurizio; Gabriella Tessitore; Gabrielle A Mandl; John A Capobianco
Journal:  Nanoscale Adv       Date:  2019-10-18

Review 3.  Photodynamic Therapy in Non-Gastrointestinal Thoracic Malignancies.

Authors:  Biniam Kidane; Dhruvin Hirpara; Kazuhiro Yasufuku
Journal:  Int J Mol Sci       Date:  2016-01-21       Impact factor: 5.923

4.  NIR-Light-Driven Generation of Reactive Oxygen Species Using Ru(II)-Decorated Lipid-Encapsulated Upconverting Nanoparticles.

Authors:  Michael S Meijer; Victorio Saez Talens; Michiel F Hilbers; Roxanne E Kieltyka; Albert M Brouwer; Marta M Natile; Sylvestre Bonnet
Journal:  Langmuir       Date:  2019-09-03       Impact factor: 3.882

Review 5.  Nanomedicine in Clinical Photodynamic Therapy for the Treatment of Brain Tumors.

Authors:  Hyung Shik Kim; Dong Yun Lee
Journal:  Biomedicines       Date:  2022-01-03
  5 in total

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