Literature DB >> 25173586

Early integration of palliative care facilitates the discontinuation of anticancer treatment in women with advanced breast or gynecologic cancers.

Fernanda Capella Rugno1, Bianca Sakamoto Ribeiro Paiva2, Carlos Eduardo Paiva3.   

Abstract

OBJECTIVES: To evaluate some health indicators in women with advanced breast or gynecological cancers (ABGCs) after discontinuation of active cancer treatment in function of the model of care received.
METHODS: This prospective study included patients who were discontinuing anticancer treatment to be followed up only with palliative care (PC). Patients who had been evaluated at least once in PC were categorized as the integrated care model (ICM); those who had not been consulted by the PC team before, as the traditional care model (TCM). Data were analyzed using chi-square, Mann-Whitney, Kaplan-Meier, and Cox regression model.
RESULTS: Among the 87 patients included in the study, 37 (42.5%) had been previously evaluated by the PC team (ICM). Patients who were followed up under an ICM exhibited better QoL (global health, p=0.02; emotional functioning, p=0.03; social functioning, p=0.01; insomnia, p=0.02) and less depression (p=0.01). The communication process had no issues in 73% of cases from the ICM group compared with 42% of cases from the TCM group (p=0.004). Patients who were not previously evaluated in PC received more chemotherapy in the last 6weeks of life compared to those who had already been evaluated (40% versus 5.9%, p=0.001). Early evaluation in PC was one of the independent prognostic factors of overall survival.
CONCLUSION: When followed up concurrently by a PC and clinical oncology team, patients reported better QoL and less depression, received less chemotherapy within the last 6weeks of life and survived longer than those followed up under a TCM.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Chemotherapy; Neoplasms; Palliative care; Transition of care

Mesh:

Substances:

Year:  2014        PMID: 25173586     DOI: 10.1016/j.ygyno.2014.08.030

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  19 in total

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Authors:  Casey M Hay; Carolyn Lefkowits; Megan Crowley-Matoka; Marie A Bakitas; Leslie H Clark; Linda R Duska; Renata R Urban; Stephanie L Creasy; Yael Schenker
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