| Literature DB >> 25173577 |
Priscila Carneiro Campos1, Marco Túlio Ribeiro Gomes1, Gabriela Guimarães1, Miriam Maria Silva Costa Franco1, Fernanda Martins Marim1, Sergio Costa Oliveira2.
Abstract
Immunity against Brucella abortus depends on the recognition of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs). Signaling pathways triggered by Brucella DNA involves TLR9, AIM2 and possibly STING and MAVS. Herein, we review the advances in B. abortus DNA sensing by host innate immune receptors and the progress in this field.Entities:
Keywords: Bacterial DNA; Brucella abortus; Cytosolic sensors; Innate immunity; TLRs
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Year: 2014 PMID： 25173577 DOI： 10.1016/j.micinf.2014.08.010
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700