| Literature DB >> 2517348 |
L Patel1, M H Sullivan, M G Elder.
Abstract
Human amnion, trophoblast and umbilical vein endothelial cells synthesise an arachidonic acid metabolite which is neither a lipoxygenase nor a cyclo-oxygenase product. It is sensitive to stimulants and inhibitors of the cytochrome-P450-dependent epoxygenase system and co-migrates on HPLC with 14,15-epoxyeicosatrienoic acid (14,15-EET), which is an epoxygenase product. The function of 14,15-EET in these reproductive tissues is unknown, but it may be involved in the maintenance of vascular function.Entities:
Mesh：
Substances：
Year: 1989 PMID： 2517348 DOI： 10.1016/0090-6980(89)90044-0
Source DB: PubMed Journal: Prostaglandins ISSN： 0090-6980