Literature DB >> 25173381

Angiogenic properties of mesenchymal stem cells in a mouse model of limb ischemia.

Leonardo Martins1, Priscila Keiko Matsumoto Martin, Sang Won Han.   

Abstract

Mesenchymal stem cells (MSCs) can be obtained from adult bone marrow and adipose tissue in large quantities and are the main cell types that contribute to recovery from ischemia because, among their biological activities, they produce several proangiogenic paracrine factors and differentiate into endothelial cells. Mouse hind limb ischemia induced by surgery is a useful animal model to study the angiogenic properties of MSCs, but it requires several precautions to be reproducible. The preparation of MSCs, the ischemic surgery, and the physiological and histological analyses are described in detail.

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Year:  2014        PMID： 25173381     DOI： 10.1007/978-1-4939-1453-1_13

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  6 in total

1.  Profound Actions of an Agonist of Growth Hormone-Releasing Hormone on Angiogenic Therapy by Mesenchymal Stem Cells.

Authors:  Qunchao Ma; Xiangyang Xia; Quanwei Tao; Kai Lu; Jian Shen; Qiyuan Xu; Xinyang Hu; Yaoliang Tang; Norman L Block; Keith A Webster; Andrew V Schally; Jian'an Wang; Hong Yu
Journal:  Arterioscler Thromb Vasc Biol       Date:  2016-02-11       Impact factor: 8.311

2.  An optimized low-pressure tourniquet murine hind limb ischemia reperfusion model: Inducing acute ischemia reperfusion injury in C57BL/6 wild type mice.

Authors:  Marius Drysch; Christoph Wallner; Sonja Verena Schmidt; Felix Reinkemeier; Johannes Maximilian Wagner; Marcus Lehnhardt; Björn Behr
Journal:  PLoS One       Date:  2019-01-24       Impact factor: 3.240

3.  Analyses of the pericyte transcriptome in ischemic skeletal muscles.

Authors:  Yuan-Chi Teng; Alfredo Leonardo Porfírio-Sousa; Giulia Magri Ribeiro; Marcela Corso Arend; Lindolfo da Silva Meirelles; Elizabeth Suchi Chen; Daniela Santoro Rosa; Sang Won Han
Journal:  Stem Cell Res Ther       Date:  2021-03-16       Impact factor: 6.832

Review 4.  Is gene therapy for limb ischemia a reality?

Authors:  Sang Won Han; Carlos Alberto Vergani; Paulo Eduardo Ocke Reis
Journal:  J Vasc Bras       Date:  2020-05-29

5.  Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF.

Authors:  Leonardo Martins; Camila Congentino Gallo; Tâmisa Seeko Bandeira Honda; Patrícia Terra Alves; Roberta Sessa Stilhano; Daniela Santoro Rosa; Timothy Jon Koh; Sang Won Han
Journal:  Stem Cell Res Ther       Date:  2020-11-06       Impact factor: 6.832

Review 6.  Mesenchymal stromal cell therapies: immunomodulatory properties and clinical progress.

Authors:  Xiaomo Wu; Ju Jiang; Zhongkai Gu; Jinyan Zhang; Yang Chen; Xiaolong Liu
Journal:  Stem Cell Res Ther       Date:  2020-08-08       Impact factor: 6.832
  6 in total

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