Literature DB >> 25172477

Transcriptomic changes in brain development.

Allissa A Dillman1, Mark R Cookson2.   

Abstract

The transcriptome changes hugely during development of the brain. Whole genes, alternate exons, and single base pair changes related to RNA editing all show differences between embryonic and mature brain. Collectively, these changes control proteomic diversity as the brain develops. Additionally, there are many changes in noncoding RNAs (miRNA and lncRNA) that interact with mRNA to influence the overall transcriptional landscape. Here, we will discuss what is known about such changes in brain development, particularly focusing on high-throughput approaches and how those can be used to infer mechanisms by which gene expression is controlled in the brain as it matures.
© 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Adult; Development; Editing; Embryo; Gene expression; RNA-Seq; Splicing

Mesh：

Year:  2014        PMID： 25172477      PMCID： PMC4662253          DOI： 10.1016/B978-0-12-801105-8.00009-6

Source DB:  PubMed          Journal:  Int Rev Neurobiol        ISSN： 0074-7742            Impact factor:   3.230


  83 in total

1.  Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2.

Authors:  M Higuchi; S Maas; F N Single; J Hartner; A Rozov; N Burnashev; D Feldmeyer; R Sprengel; P H Seeburg
Journal:  Nature       Date:  2000-07-06       Impact factor: 49.962

2.  A microRNA array reveals extensive regulation of microRNAs during brain development.

Authors:  Anna M Krichevsky; Kevin S King; Christine P Donahue; Konstantin Khrapko; Kenneth S Kosik
Journal:  RNA       Date:  2003-10       Impact factor: 4.942

3.  The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing.

Authors:  Eugene V Makeyev; Jiangwen Zhang; Monica A Carrasco; Tom Maniatis
Journal:  Mol Cell       Date:  2007-08-03       Impact factor: 17.970

4.  Gene expression profiling during the embryonic development of mouse brain using an oligonucleotide-based microarray system.

Authors:  Tohru Matsuki; Gen Hori; Teiichi Furuichi
Journal:  Brain Res Mol Brain Res       Date:  2005-03-23

5.  DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain.

Authors:  T Takizawa; K Nakashima; M Namihira; W Ochiai; A Uemura; M Yanagisawa; N Fujita; M Nakao; T Taga
Journal:  Dev Cell       Date:  2001-12       Impact factor: 12.270

Review 6.  Effects of DNA methylation on DNA-binding proteins and gene expression.

Authors:  P H Tate; A P Bird
Journal:  Curr Opin Genet Dev       Date:  1993-04       Impact factor: 5.578

7.  Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay.

Authors:  Dilek Colak; Sheng-Jian Ji; Bo T Porse; Samie R Jaffrey
Journal:  Cell       Date:  2013-06-06       Impact factor: 41.582

Review 8.  miRNAs in development and pathogenesis of the nervous system.

Authors:  Jakub S Nowak; Gracjan Michlewski
Journal:  Biochem Soc Trans       Date:  2013-08       Impact factor: 5.407

Review 9.  Non-coding RNA interact to regulate neuronal development and function.

Authors:  Bharat R Iyengar; Ashwani Choudhary; Mayuresh A Sarangdhar; K V Venkatesh; Chetan J Gadgil; Beena Pillai
Journal:  Front Cell Neurosci       Date:  2014-02-24       Impact factor: 5.505

10.  Widespread splicing changes in human brain development and aging.

Authors:  Pavel Mazin; Jieyi Xiong; Xiling Liu; Zheng Yan; Xiaoyu Zhang; Mingshuang Li; Liu He; Mehmet Somel; Yuan Yuan; Yi-Ping Phoebe Chen; Na Li; Yuhui Hu; Ning Fu; Zhibin Ning; Rong Zeng; Hongyi Yang; Wei Chen; Mikhail Gelfand; Philipp Khaitovich
Journal:  Mol Syst Biol       Date:  2013       Impact factor: 11.429
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  3 in total

1.  Identification of Natural Antisense Transcripts in Mouse Brain and Their Association With Autism Spectrum Disorder Risk Genes.

Authors:  Baran Koç; Geoffrey Fucile; Roland Schmucki; Nicolas Giroud; Tobias Bergauer; Benjamin J Hall
Journal:  Front Mol Neurosci       Date:  2021-02-25       Impact factor: 5.639

2.  DNA Methylation Regulates Transcription Factor-Specific Neurodevelopmental but Not Sexually Dimorphic Gene Expression Dynamics in Zebra Finch Telencephalon.

Authors:  Jolien Diddens; Louis Coussement; Carolina Frankl-Vilches; Gaurav Majumdar; Sandra Steyaert; Sita M Ter Haar; Jeroen Galle; Ellen De Meester; Sarah De Keulenaer; Wim Van Criekinge; Charlotte A Cornil; Jacques Balthazart; Annemie Van Der Linden; Tim De Meyer; Wim Vanden Berghe
Journal:  Front Cell Dev Biol       Date:  2021-03-19

3.  Single-cell transcriptomics of the developing lateral geniculate nucleus reveals insights into circuit assembly and refinement.

Authors:  Brian T Kalish; Lucas Cheadle; Sinisa Hrvatin; M Aurel Nagy; Samuel Rivera; Megan Crow; Jesse Gillis; Rory Kirchner; Michael E Greenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2018-01-17       Impact factor: 11.205
  3 in total

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