Eric J Sigler1, Jorge I Calzada. 1. *Ophthalmic Consultants of Long Island, Rockville Center, New York; and †Division of Vitreoretinal Surgery, Charles Retina Institute, Memphis, Tennessee.
Abstract
PURPOSE: To describe the structural characteristics of retinal angiomatous proliferation and chorioretinal anastomosis in childhood Coats disease and redefine the previously described macular fibrosis. METHODS: Prospective observational case series of consecutive patients with Coats disease examined over a 1-year study period. Multimodal imaging, including color fundus photography, wide-field fluorescein angiography, and spectral domain optical coherence tomography, was used to identify the features of macular retinal angiomatous proliferation and chorioretinal anastomosis. RESULTS: Retinal angiomatous proliferation and chorioretinal anastomosis were present in 5 of 21 patients with Coats disease (24%). The lesions appeared as well demarcated, nodular retinal pigment epithelial detachments surrounded by exudate, with retinal vessels continuous with the underlying choroidal neovascularization. CONCLUSION: Retinal angiomatous proliferation and chorioretinal anastomoses are features observed in a number of children (24% in the present series) with Coats disease and macular involvement. This lesion represents a distinct macular variant of Coats disease that underlies at least a proportion (all in the present series) of the previously described "macular fibrosis" and "subretinal mounds."
PURPOSE: To describe the structural characteristics of retinal angiomatous proliferation and chorioretinal anastomosis in childhood Coats disease and redefine the previously described macular fibrosis. METHODS: Prospective observational case series of consecutive patients with Coats disease examined over a 1-year study period. Multimodal imaging, including color fundus photography, wide-field fluorescein angiography, and spectral domain optical coherence tomography, was used to identify the features of macular retinal angiomatous proliferation and chorioretinal anastomosis. RESULTS:Retinal angiomatous proliferation and chorioretinal anastomosis were present in 5 of 21 patients with Coats disease (24%). The lesions appeared as well demarcated, nodular retinal pigment epithelial detachments surrounded by exudate, with retinal vessels continuous with the underlying choroidal neovascularization. CONCLUSION:Retinal angiomatous proliferation and chorioretinal anastomoses are features observed in a number of children (24% in the present series) with Coats disease and macular involvement. This lesion represents a distinct macular variant of Coats disease that underlies at least a proportion (all in the present series) of the previously described "macular fibrosis" and "subretinal mounds."
Authors: Hyun Goo Kang; Jung Dong Kim; Eun Young Choi; Suk Ho Byeon; Sung Soo Kim; Hyoung Jun Koh; Min Kim Journal: Sci Rep Date: 2021-03-17 Impact factor: 4.379
Authors: Marcel V Alavi; Mao Mao; Bradley T Pawlikowski; Manana Kvezereli; Jacque L Duncan; Richard T Libby; Simon W M John; Douglas B Gould Journal: Sci Rep Date: 2016-01-27 Impact factor: 4.379