Literature DB >> 25170405

The effect of honey gel on abdominal wound healing in cesarean section: a triple blind randomized clinical trial.

Maryam Nikpour1, Marjan Ahmad Shirvani2, Mohammad Azadbakht3, Roya Zanjani4, Ensieh Mousavi5.   

Abstract

OBJECTIVE: To assess whether honey can accelerate the wound healing in women undergoing cesarean section.
METHODS: This was a triple blinded randomized prospective clinical trial. Women with cesarean section were randomly designated as drug (37 cases) and placebo (38 cases) groups. The drug group received local honey gel 25% while the placebo group received similar free-honey gel on abdominal cesarean incision twice a day for 14 days. REEDA scale (Redness, Edema, Ecchymosis, Discharge and Approximation of wound edges) was used to assess wound healing.
RESULTS: The mean REEDA was 2.27 ± 2.46 and 3.91 ± 2.74 (p=0.008) on the 7(th) day and 0.47 ± 0.84 and 1.59± 1.95 (p=0.002) on the 14(th) day for the drug and placebo groups, respectively. Redness, edema and hematoma in the drug group were significantly lower on the 7(th) and 14(th) days.
CONCLUSION: Honey was effective in healing the cesarean section incision. Using topical honey is suggested as a natural product with rare side effects in order to reduce the complications of cesarean wounds.

Entities:  

Keywords:  Cesarean; Healing; Honey; Incision; Wound

Year:  2014        PMID: 25170405      PMCID: PMC4137579          DOI: 10.5001/omj.2014.68

Source DB:  PubMed          Journal:  Oman Med J        ISSN: 1999-768X


  27 in total

Review 1.  Re-introducing honey in the management of wounds and ulcers - theory and practice.

Authors:  Peter C Molan
Journal:  Ostomy Wound Manage       Date:  2002-11       Impact factor: 2.629

Review 2.  Honey: a potent agent for wound healing?

Authors:  P E Lusby; A Coombes; J M Wilkinson
Journal:  J Wound Ostomy Continence Nurs       Date:  2002-11       Impact factor: 1.741

3.  Subcutaneous stitch closure versus subcutaneous drain to prevent wound disruption after cesarean delivery: a randomized clinical trial.

Authors:  Everett F Magann; Suneet P Chauhan; Sheryl Rodts-Palenik; Laura Bufkin; James N Martin; John C Morrison
Journal:  Am J Obstet Gynecol       Date:  2002-06       Impact factor: 8.661

4.  An Investigation into Perioperative Antibiotic Use during Lower Segment Caesarean Sections (LSCS) in Four Hospitals in Oman.

Authors:  Brian Gunn; Sayed Ali; Ahmed Abdo-Rabbo; Batool Suleiman
Journal:  Oman Med J       Date:  2009-07

5.  REEDA: evaluating postpartum healing.

Authors:  N Davidson
Journal:  J Nurse Midwifery       Date:  1974

Review 6.  The use of honey for wound care management: a traditional remedy revisited.

Authors:  Jennifer Chang; Norma G Cuellar
Journal:  Home Healthc Nurse       Date:  2009-05

7.  Honey-medicated dressing: transformation of an ancient remedy into modern therapy.

Authors:  A Kalam J Ahmed; M Johannes Hoekstra; J Joris Hage; Refaat B Karim
Journal:  Ann Plast Surg       Date:  2003-02       Impact factor: 1.539

Review 8.  Honey in the management of infections.

Authors:  Nicholas Namias
Journal:  Surg Infect (Larchmt)       Date:  2003       Impact factor: 2.150

Review 9.  Systematic review of the use of honey as a wound dressing.

Authors:  O A Moore; L A Smith; F Campbell; K Seers; H J McQuay; R A Moore
Journal:  BMC Complement Altern Med       Date:  2001-06-04       Impact factor: 3.659

10.  Antimicrobial activity of two South African honeys produced from indigenous Leucospermum cordifolium and Erica species on selected micro-organisms.

Authors:  Nicolaas J Basson; Sias R Grobler
Journal:  BMC Complement Altern Med       Date:  2008-07-15       Impact factor: 3.659

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  7 in total

1.  Does application of honey improve surgical outcome in pilonidal cyst excision with secondary intention healing? A prospective randomized placebo-controlled clinical trial.

Authors:  Vahid Salehi; Mohammad Javad Yavari Barhaghtalab; Saadat Mehrabi; Aida Iraji; Seyed Alimohammad Sadat; Seyed Hadi Yusefi; Jan Mohamad Malekzadeh
Journal:  Perioper Med (Lond)       Date:  2022-01-10

Review 2.  Effect of Complementary Medicine on Pain Relief and Wound Healing after Cesarean Section: A Systematic Review.

Authors:  Azin Niazi; Maryam Moradi; Vahid Reza Askari; Neda Sharifi
Journal:  J Pharmacopuncture       Date:  2021-06-30

3.  Effects of Selected Egyptian Honeys on the Cellular Ultrastructure and the Gene Expression Profile of Escherichia coli.

Authors:  Reham Wasfi; Walid F Elkhatib; Ahmed S Khairalla
Journal:  PLoS One       Date:  2016-03-08       Impact factor: 3.240

Review 4.  Wound Healing Properties of Selected Natural Products.

Authors:  Nurul 'Izzah Ibrahim; Sok Kuan Wong; Isa Naina Mohamed; Norazlina Mohamed; Kok-Yong Chin; Soelaiman Ima-Nirwana; Ahmad Nazrun Shuid
Journal:  Int J Environ Res Public Health       Date:  2018-10-25       Impact factor: 3.390

5.  The impact of calendula ointment on cesarean wound healing: A randomized controlled clinical trial.

Authors:  Fereshteh Jahdi; Akram Haghighi Khabbaz; Maryam Kashian; Mohsen Taghizadeh; Hamid Haghani
Journal:  J Family Med Prim Care       Date:  2018 Sep-Oct

6.  Enhanced electroscalpel incisional wound healing potential of honey in wistar rats.

Authors:  David O Eyarefe; David I Kuforiji; Theophilus A Jarikre; Benjamin O Emikpe
Journal:  Int J Vet Sci Med       Date:  2017-11-13

Review 7.  Anti-Inflammatory and Restorative Effects of Olives in Topical Application.

Authors:  Mahdiyeh Taheri; Leila Amiri-Farahani
Journal:  Dermatol Res Pract       Date:  2021-06-26
  7 in total

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