An effective pulse sequence for simultaneous HIFU insonation and monitoring.

The HIFU interference cancellation method using pulse inversion is useful for real-time treatment monitoring; however, this method suffers from residual interference when a high duty cycle is employed. In this paper, a pulse sequence is proposed to overcome the problem. It was experimentally verified that all interference could be removed using the pulse sequence. This implies that the HIFU interference cancellation method with the pulse sequence can be utilized for simultaneous HIFU insonation and monitoring under any duty cycle condition.