Literature DB >> 25167156

Rapid prototyping fabrication of focused ultrasound transducers.

Yohan Kim, Adam D Maxwell, Timothy L Hall, Zhen Xu, Kuang-Wei Lin, Charles A Cain.   

Abstract

Rapid prototyping (RP) fabrication techniques are currently widely used in diverse industrial and medical fields, providing substantial advantages in development time and costs in comparison to more traditional manufacturing processes. This paper presents a new method for the fabrication of high-intensity focused ultrasound transducers using RP technology. The construction of a large-aperture hemispherical transducer designed by computer software is described to demonstrate the process. The transducer was conceived as a modular design consisting of 32 individually focused 50.8-mm (2-in) PZT-8 element modules distributed in a 300-mm hemispherical scaffold with a geometric focus of 150 mm. The entire structure of the array, including the module housings and the hemispherical scaffold was fabricated through a stereolithography (SLA) system using a proprietary photopolymer. The PZT elements were bonded to the lenses through a quarter-wave tungsten-epoxy matching layer developed in-house specifically for this purpose. Modules constructed in this manner displayed a high degree of electroacoustic consistency, with an electrical impedance mean and standard deviation of 109 ± 10.2 Ω for the 32 elements. Time-of-flight measurements for individually pulsed modules mounted on the hemispherical scaffold showed that all pulses arrived at the focus within a 350 ns range, indicating a good degree of element alignment. Pressure profile measurements of the fully assembled transducer also showed close agreement with simulated results. The measured focal beam FWHM dimensions were 1.9 × 4.0 mm (1.9 × 3.9 mm simulated) in the transversal and axial directions respectively. Total material expenses associated with the construction of the transducer were approximately 5000 USD (as of 2011). The versatility and lower fabrication costs afforded by RP methods may be beneficial in the development of complex transducer geometries suitable for a variety of research and clinical applications.

Mesh:

Year:  2014        PMID: 25167156     DOI: 10.1109/TUFFC.2014.3070

Source DB:  PubMed          Journal:  IEEE Trans Ultrason Ferroelectr Freq Control        ISSN: 0885-3010            Impact factor:   2.725


  21 in total

1.  Effect of Frequency and Focal Spacing on Transcranial Histotripsy Clot Liquefaction, Using Electronic Focal Steering.

Authors:  Tyler Gerhardson; Jonathan R Sukovich; Aditya S Pandey; Timothy L Hall; Charles A Cain; Zhen Xu
Journal:  Ultrasound Med Biol       Date:  2017-07-14       Impact factor: 2.998

2.  Enhanced Shock Scattering Histotripsy With Pseudomonopolar Ultrasound Pulses.

Authors:  Yige Li; Timothy L Hall; Zhen Xu; Charles A Cain
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2019-04-15       Impact factor: 2.725

Review 3.  For Whom the Bubble Grows: Physical Principles of Bubble Nucleation and Dynamics in Histotripsy Ultrasound Therapy.

Authors:  Kenneth B Bader; Eli Vlaisavljevich; Adam D Maxwell
Journal:  Ultrasound Med Biol       Date:  2019-03-26       Impact factor: 2.998

4.  A Prototype Therapy System for Transcutaneous Application of Boiling Histotripsy.

Authors:  Adam D Maxwell; Petr V Yuldashev; Wayne Kreider; Tatiana D Khokhlova; George R Schade; Timothy L Hall; Oleg A Sapozhnikov; Michael R Bailey; Vera A Khokhlova
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2017-08-14       Impact factor: 2.725

5.  Design, fabrication, and characterization of broad beam transducers for fragmenting large renal calculi with burst wave lithotripsy.

Authors:  Akshay Randad; Mohamed A Ghanem; Michael R Bailey; Adam D Maxwell
Journal:  J Acoust Soc Am       Date:  2020-07       Impact factor: 1.840

6.  Design of HIFU Transducers for Generating Specified Nonlinear Ultrasound Fields.

Authors:  Pavel B Rosnitskiy; Petr V Yuldashev; Oleg A Sapozhnikov; Adam D Maxwell; Wayne Kreider; Michael R Bailey; Vera A Khokhlova
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2016-10-20       Impact factor: 2.725

7.  Non-invasive, Rapid Ablation of Tissue Volume Using Histotripsy.

Authors:  Jonathan E Lundt; Steven P Allen; Jiaqi Shi; Timothy L Hall; Charles A Cain; Zhen Xu
Journal:  Ultrasound Med Biol       Date:  2017-09-19       Impact factor: 2.998

8.  DESIGN OF A TRANSDUCER FOR FRAGMENTING LARGE KIDNEY STONES USING BURST WAVE LITHOTRIPSY.

Authors:  Akshay P Randad; Mohamed A Ghanem; Michael R Bailey; Adam D Maxwell
Journal:  Proc Meet Acoust       Date:  2019-01-09

9.  Neuromodulation Management of Chronic Neuropathic Pain in The Central Nervous system.

Authors:  Kai Yu; Xiaodan Niu; Bin He
Journal:  Adv Funct Mater       Date:  2020-06-10       Impact factor: 18.808

10.  Histotripsy Liquefaction of Large Hematomas.

Authors:  Tatiana D Khokhlova; Wayne L Monsky; Yasser A Haider; Adam D Maxwell; Yak-Nam Wang; Thomas J Matula
Journal:  Ultrasound Med Biol       Date:  2016-04-25       Impact factor: 2.998

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