Literature DB >> 25165554

Management of community-acquired pneumonia in older adults.

Antonella F Simonetti1, Diego Viasus2, Carolina Garcia-Vidal2, Jordi Carratalà3.   

Abstract

Community-acquired pneumonia (CAP) is an increasing problem among the elderly. Multiple factors related to ageing, such as comorbidities, nutritional status and swallowing dysfunction have been implicated in the increased incidence of CAP in the older population. Moreover, mortality in patients with CAP rises dramatically with increasing age. Streptococcus pneumoniae is still the most common pathogen among the elderly, although CAP may also be caused by drug-resistant microorganisms and aspiration pneumonia. Furthermore, in the elderly CAP has a different clinical presentation, often lacking the typical acute symptoms observed in younger adults, due to the lower local and systemic inflammatory response. Several independent prognostic factors for mortality in the elderly have been identified, including factors related to pneumonia severity, inadequate response to infection, and low functional status. CAP scores and biomarkers have lower prognostic value in the elderly, and so there is a need to find new scales or to set new cut-off points for current scores in this population. Adherence to the current guidelines for CAP has a significant beneficial impact on clinical outcomes in elderly patients. Particular attention should also be paid to nutritional status, fluid administration, functional status, and comorbidity stabilizing therapy in this group of frail patients. This article presents an up-to-date review of the main aspects of CAP in elderly patients, including epidemiology, causative organisms, clinical features, and prognosis, and assesses key points for best practices for the management of the disease.

Entities:  

Keywords:  clinical features; community-acquired pneumonia; elderly; etiology; management; prognosis; treatment

Year:  2014        PMID: 25165554      PMCID: PMC4072047          DOI: 10.1177/2049936113518041

Source DB:  PubMed          Journal:  Ther Adv Infect Dis        ISSN: 2049-9361


  81 in total

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