Literature DB >> 25162997

NDRG1 as a molecular target to inhibit the epithelial-mesenchymal transition: the case for developing inhibitors of metastasis.

Sumit Sahni1, Sukriti Krishan, Des R Richardson.   

Abstract

Entities:  

Keywords:  NDRG1; epithelial–mesenchymal transition; iron; metastasis; thiosemicarbazones

Mesh:

Substances:

Year:  2014        PMID: 25162997     DOI: 10.4155/fmc.14.80

Source DB:  PubMed          Journal:  Future Med Chem        ISSN: 1756-8919            Impact factor:   3.808


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  5 in total

1.  LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene.

Authors:  Susanna Ambrosio; Stefano Amente; Carmen D Saccà; Mario Capasso; Raffaele A Calogero; Luigi Lania; Barbara Majello
Journal:  Oncotarget       Date:  2017-01-17

2.  MORC2 promotes development of an aggressive colorectal cancer phenotype through inhibition of NDRG1.

Authors:  Jiao Liu; Yangguang Shao; Yuxin He; Ke Ning; Xi Cui; Furong Liu; Zhenning Wang; Feng Li
Journal:  Cancer Sci       Date:  2018-12-21       Impact factor: 6.716

3.  Microrchidia family CW‑type zinc finger 2 promotes the proliferation, invasion, migration and epithelial‑mesenchymal transition of glioma by regulating PTEN/PI3K/AKT signaling via binding to N‑myc downstream regulated gene 1 promoter.

Authors:  Jing Zhang; Yunna Yang; Yipeng Dong; Cang Liu
Journal:  Int J Mol Med       Date:  2021-12-16       Impact factor: 4.101

Review 4.  Emerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancer.

Authors:  Wei Hu; Chongxi Fan; Peng Jiang; Zhiqiang Ma; Xiaolong Yan; Shouyin Di; Shuai Jiang; Tian Li; Yedong Cheng; Yang Yang
Journal:  Oncotarget       Date:  2016-01-05

5.  Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types.

Authors:  Rayan S Moussa; Zaklina Kovacevic; Des R Richardson
Journal:  Oncotarget       Date:  2015-10-06
  5 in total

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