Christopher Orsborne1, Matthias Schmitt2. 1. Department of Cardiology, University Hospital of South Manchester, Southmoor Road, Manchester M23 9LT, UK chris.orsborne@doctors.net.uk. 2. Department of Cardiology, University Hospital of South Manchester, Southmoor Road, Manchester M23 9LT, UK University of Manchester, Oxford Road, Manchester M13 9PL, UK.