Literature DB >> 2516082

Cispentacin, a new antifungal antibiotic. I. Production, isolation, physico-chemical properties and structure.

M Konishi1, M Nishio, K Saitoh, T Miyaki, T Oki, H Kawaguchi.   

Abstract

A new antibiotic, cispentacin, was isolated from the culture broth of a Bacillus cereus strain, L450-B2. The antibiotic is water-soluble and amphoteric; its structure was determined by spectroscopic analysis and chemical synthesis to be (1R,2S)-2-aminocyclopentane-1-carboxylic acid. Cispentacin demonstrated only weak in vitro activity against certain fungi but strong protection of mice from lethal infection of Candida albicans A9540.

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Year:  1989        PMID： 2516082     DOI： 10.7164/antibiotics.42.1749

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  17 in total

1.  In vitro activity and in vivo efficacy of icofungipen (PLD-118), a novel oral antifungal agent, against the pathogenic yeast Candida albicans.

Authors:  Andreja Hasenoehrl; Tatjana Galic; Gabrijela Ergovic; Natasa Marsic; Mihael Skerlev; Joachim Mittendorf; Ulrich Geschke; Axel Schmidt; Wolfgang Schoenfeld
Journal:  Antimicrob Agents Chemother       Date:  2006-09       Impact factor: 5.191

Review 2.  Antifungal agents: chemotherapeutic targets and immunologic strategies.

Authors:  N H Georgopapadakou; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  1996-02       Impact factor: 5.191

3.  The Amipurimycin and Miharamycin Biosynthetic Gene Clusters: Unraveling the Origins of 2-Aminopurinyl Peptidyl Nucleoside Antibiotics.

Authors:  Anthony J Romo; Taro Shiraishi; Hideo Ikeuchi; Geng-Min Lin; Yujie Geng; Yu-Hsuan Lee; Priscilla H Liem; Tianlu Ma; Yasushi Ogasawara; Kazuo Shin-Ya; Makoto Nishiyama; Tomohisa Kuzuyama; Hung-Wen Liu
Journal:  J Am Chem Soc       Date:  2019-09-03       Impact factor: 15.419

4.  Molecular mode of action of the antifungal beta-amino acid BAY 10-8888.

Authors:  K Ziegelbauer; P Babczinski; W Schönfeld
Journal:  Antimicrob Agents Chemother       Date:  1998-09       Impact factor: 5.191

Review 5.  The Mechanistic Targets of Antifungal Agents: An Overview.

Authors:  Tryphon K Mazu; Barbara A Bricker; Hernan Flores-Rozas; Seth Y Ablordeppey
Journal:  Mini Rev Med Chem       Date:  2016       Impact factor: 3.862

6.  Decreased accumulation or increased isoleucyl-tRNA synthetase activity confers resistance to the cyclic beta-amino acid BAY 10-8888 in Candida albicans and Candida tropicalis.

Authors:  K Ziegelbauer
Journal:  Antimicrob Agents Chemother       Date:  1998-07       Impact factor: 5.191

Review 7.  Amino Acid Based Antimicrobial Agents - Synthesis and Properties.

Authors:  Michał G Nowak; Andrzej S Skwarecki; Maria J Milewska
Journal:  ChemMedChem       Date:  2021-10-01       Impact factor: 3.540

8.  Antifungals: need to search for a new molecular target.

Authors:  A T Sangamwar; U D Deshpande; S S Pekamwar
Journal:  Indian J Pharm Sci       Date:  2008 Jul-Aug       Impact factor: 0.975

9.  Efficient continuous-flow synthesis of novel 1,2,3-triazole-substituted β-aminocyclohexanecarboxylic acid derivatives with gram-scale production.

Authors:  Sándor B Otvös; Adám Georgiádes; István M Mándity; Lóránd Kiss; Ferenc Fülöp
Journal:  Beilstein J Org Chem       Date:  2013-07-29       Impact factor: 2.883

Review 10.  Structural analyses of the malaria parasite aminoacyl-tRNA synthetases provide new avenues for antimalarial drug discovery.

Authors:  Jyoti Chhibber-Goel; Manickam Yogavel; Amit Sharma
Journal:  Protein Sci       Date:  2021-09       Impact factor: 6.993
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