Literature DB >> 25157507

The epigenetic landscape of Alzheimer's disease.

Jenny Lord1, Carlos Cruchaga2.   

Abstract

Two independent epigenome-wide association studies of Alzheimer’s disease cohorts have identified overlapping methylation signals in four loci, ANK1, RPL13, RHBDF2 and CDH23, not previously associated with Alzheimer’s disease. These studies also suggest that epigenetic changes contribute more to Alzheimer’s disease than expected.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25157507      PMCID： PMC5472058          DOI： 10.1038/nn.3792

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN： 1097-6256            Impact factor:   24.884


  14 in total

1.  Distinct DNA methylation changes highly correlated with chronological age in the human brain.

Authors:  Dena G Hernandez; Michael A Nalls; J Raphael Gibbs; Sampath Arepalli; Marcel van der Brug; Sean Chong; Matthew Moore; Dan L Longo; Mark R Cookson; Bryan J Traynor; Andrew B Singleton
Journal:  Hum Mol Genet       Date:  2011-01-07       Impact factor: 6.150

Review 2.  From promises to practical strategies in epigenetic epidemiology.

Authors:  Jonathan Mill; Bastiaan T Heijmans
Journal:  Nat Rev Genet       Date:  2013-07-02       Impact factor: 53.242

3.  Forecasting the global burden of Alzheimer's disease.

Authors:  Ron Brookmeyer; Elizabeth Johnson; Kathryn Ziegler-Graham; H Michael Arrighi
Journal:  Alzheimers Dement       Date:  2007-07       Impact factor: 21.566

Review 4.  Epigenomics of Alzheimer's disease.

Authors:  David A Bennett; Lei Yu; Jingyun Yang; Gyan P Srivastava; Cristin Aubin; Philip L De Jager
Journal:  Transl Res       Date:  2014-05-16       Impact factor: 7.012

5.  Genetics of Alzheimer disease in the pre- and post-GWAS era.

Authors:  Nilüfer Ertekin-Taner
Journal:  Alzheimers Res Ther       Date:  2010-03-05       Impact factor: 6.982

6.  Genome-wide analysis of genetic loci associated with Alzheimer disease.

Authors:  Sudha Seshadri; Annette L Fitzpatrick; M Arfan Ikram; Anita L DeStefano; Vilmundur Gudnason; Merce Boada; Joshua C Bis; Albert V Smith; Minerva M Carassquillo; Jean Charles Lambert; Denise Harold; Elisabeth M C Schrijvers; Reposo Ramirez-Lorca; Stephanie Debette; W T Longstreth; A Cecile J W Janssens; V Shane Pankratz; Jean François Dartigues; Paul Hollingworth; Thor Aspelund; Isabel Hernandez; Alexa Beiser; Lewis H Kuller; Peter J Koudstaal; Dennis W Dickson; Christophe Tzourio; Richard Abraham; Carmen Antunez; Yangchun Du; Jerome I Rotter; Yurii S Aulchenko; Tamara B Harris; Ronald C Petersen; Claudine Berr; Michael J Owen; Jesus Lopez-Arrieta; Badri N Varadarajan; James T Becker; Fernando Rivadeneira; Michael A Nalls; Neill R Graff-Radford; Dominique Campion; Sanford Auerbach; Kenneth Rice; Albert Hofman; Palmi V Jonsson; Helena Schmidt; Mark Lathrop; Thomas H Mosley; Rhoda Au; Bruce M Psaty; Andre G Uitterlinden; Lindsay A Farrer; Thomas Lumley; Agustin Ruiz; Julie Williams; Philippe Amouyel; Steve G Younkin; Philip A Wolf; Lenore J Launer; Oscar L Lopez; Cornelia M van Duijn; Monique M B Breteler
Journal:  JAMA       Date:  2010-05-12       Impact factor: 56.272

7.  Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood.

Authors:  Matthew N Davies; Manuela Volta; Ruth Pidsley; Katie Lunnon; Abhishek Dixit; Simon Lovestone; Cristian Coarfa; R Alan Harris; Aleksandar Milosavljevic; Claire Troakes; Safa Al-Sarraj; Richard Dobson; Leonard C Schalkwyk; Jonathan Mill
Journal:  Genome Biol       Date:  2012-06-15       Impact factor: 13.583

8.  Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

Authors:  Paul Hollingworth; Denise Harold; Rebecca Sims; Amy Gerrish; Jean-Charles Lambert; Minerva M Carrasquillo; Richard Abraham; Marian L Hamshere; Jaspreet Singh Pahwa; Valentina Moskvina; Kimberley Dowzell; Nicola Jones; Alexandra Stretton; Charlene Thomas; Alex Richards; Dobril Ivanov; Caroline Widdowson; Jade Chapman; Simon Lovestone; John Powell; Petroula Proitsi; Michelle K Lupton; Carol Brayne; David C Rubinsztein; Michael Gill; Brian Lawlor; Aoibhinn Lynch; Kristelle S Brown; Peter A Passmore; David Craig; Bernadette McGuinness; Stephen Todd; Clive Holmes; David Mann; A David Smith; Helen Beaumont; Donald Warden; Gordon Wilcock; Seth Love; Patrick G Kehoe; Nigel M Hooper; Emma R L C Vardy; John Hardy; Simon Mead; Nick C Fox; Martin Rossor; John Collinge; Wolfgang Maier; Frank Jessen; Eckart Rüther; Britta Schürmann; Reiner Heun; Heike Kölsch; Hendrik van den Bussche; Isabella Heuser; Johannes Kornhuber; Jens Wiltfang; Martin Dichgans; Lutz Frölich; Harald Hampel; John Gallacher; Michael Hüll; Dan Rujescu; Ina Giegling; Alison M Goate; John S K Kauwe; Carlos Cruchaga; Petra Nowotny; John C Morris; Kevin Mayo; Kristel Sleegers; Karolien Bettens; Sebastiaan Engelborghs; Peter P De Deyn; Christine Van Broeckhoven; Gill Livingston; Nicholas J Bass; Hugh Gurling; Andrew McQuillin; Rhian Gwilliam; Panagiotis Deloukas; Ammar Al-Chalabi; Christopher E Shaw; Magda Tsolaki; Andrew B Singleton; Rita Guerreiro; Thomas W Mühleisen; Markus M Nöthen; Susanne Moebus; Karl-Heinz Jöckel; Norman Klopp; H-Erich Wichmann; V Shane Pankratz; Sigrid B Sando; Jan O Aasly; Maria Barcikowska; Zbigniew K Wszolek; Dennis W Dickson; Neill R Graff-Radford; Ronald C Petersen; Cornelia M van Duijn; Monique M B Breteler; M Arfan Ikram; Anita L DeStefano; Annette L Fitzpatrick; Oscar Lopez; Lenore J Launer; Sudha Seshadri; Claudine Berr; Dominique Campion; Jacques Epelbaum; Jean-François Dartigues; Christophe Tzourio; Annick Alpérovitch; Mark Lathrop; Thomas M Feulner; Patricia Friedrich; Caterina Riehle; Michael Krawczak; Stefan Schreiber; Manuel Mayhaus; S Nicolhaus; Stefan Wagenpfeil; Stacy Steinberg; Hreinn Stefansson; Kari Stefansson; Jon Snaedal; Sigurbjörn Björnsson; Palmi V Jonsson; Vincent Chouraki; Benjamin Genier-Boley; Mikko Hiltunen; Hilkka Soininen; Onofre Combarros; Diana Zelenika; Marc Delepine; Maria J Bullido; Florence Pasquier; Ignacio Mateo; Ana Frank-Garcia; Elisa Porcellini; Olivier Hanon; Eliecer Coto; Victoria Alvarez; Paolo Bosco; Gabriele Siciliano; Michelangelo Mancuso; Francesco Panza; Vincenzo Solfrizzi; Benedetta Nacmias; Sandro Sorbi; Paola Bossù; Paola Piccardi; Beatrice Arosio; Giorgio Annoni; Davide Seripa; Alberto Pilotto; Elio Scarpini; Daniela Galimberti; Alexis Brice; Didier Hannequin; Federico Licastro; Lesley Jones; Peter A Holmans; Thorlakur Jonsson; Matthias Riemenschneider; Kevin Morgan; Steven G Younkin; Michael J Owen; Michael O'Donovan; Philippe Amouyel; Julie Williams
Journal:  Nat Genet       Date:  2011-04-03       Impact factor: 38.330

9.  Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

Authors:  J C Lambert; C A Ibrahim-Verbaas; D Harold; A C Naj; R Sims; C Bellenguez; A L DeStafano; J C Bis; G W Beecham; B Grenier-Boley; G Russo; T A Thorton-Wells; N Jones; A V Smith; V Chouraki; C Thomas; M A Ikram; D Zelenika; B N Vardarajan; Y Kamatani; C F Lin; A Gerrish; H Schmidt; B Kunkle; M L Dunstan; A Ruiz; M T Bihoreau; S H Choi; C Reitz; F Pasquier; C Cruchaga; D Craig; N Amin; C Berr; O L Lopez; P L De Jager; V Deramecourt; J A Johnston; D Evans; S Lovestone; L Letenneur; F J Morón; D C Rubinsztein; G Eiriksdottir; K Sleegers; A M Goate; N Fiévet; M W Huentelman; M Gill; K Brown; M I Kamboh; L Keller; P Barberger-Gateau; B McGuiness; E B Larson; R Green; A J Myers; C Dufouil; S Todd; D Wallon; S Love; E Rogaeva; J Gallacher; P St George-Hyslop; J Clarimon; A Lleo; A Bayer; D W Tsuang; L Yu; M Tsolaki; P Bossù; G Spalletta; P Proitsi; J Collinge; S Sorbi; F Sanchez-Garcia; N C Fox; J Hardy; M C Deniz Naranjo; P Bosco; R Clarke; C Brayne; D Galimberti; M Mancuso; F Matthews; S Moebus; P Mecocci; M Del Zompo; W Maier; H Hampel; A Pilotto; M Bullido; F Panza; P Caffarra; B Nacmias; J R Gilbert; M Mayhaus; L Lannefelt; H Hakonarson; S Pichler; M M Carrasquillo; M Ingelsson; D Beekly; V Alvarez; F Zou; O Valladares; S G Younkin; E Coto; K L Hamilton-Nelson; W Gu; C Razquin; P Pastor; I Mateo; M J Owen; K M Faber; P V Jonsson; O Combarros; M C O'Donovan; L B Cantwell; H Soininen; D Blacker; S Mead; T H Mosley; D A Bennett; T B Harris; L Fratiglioni; C Holmes; R F de Bruijn; P Passmore; T J Montine; K Bettens; J I Rotter; A Brice; K Morgan; T M Foroud; W A Kukull; D Hannequin; J F Powell; M A Nalls; K Ritchie; K L Lunetta; J S Kauwe; E Boerwinkle; M Riemenschneider; M Boada; M Hiltuenen; E R Martin; R Schmidt; D Rujescu; L S Wang; J F Dartigues; R Mayeux; C Tzourio; A Hofman; M M Nöthen; C Graff; B M Psaty; L Jones; J L Haines; P A Holmans; M Lathrop; M A Pericak-Vance; L J Launer; L A Farrer; C M van Duijn; C Van Broeckhoven; V Moskvina; S Seshadri; J Williams; G D Schellenberg; P Amouyel
Journal:  Nat Genet       Date:  2013-10-27       Impact factor: 38.330

10.  Independent component analysis of Alzheimer's DNA microarray gene expression data.

Authors:  Wei Kong; Xiaoyang Mou; Qingzhong Liu; Zhongxue Chen; Charles R Vanderburg; Jack T Rogers; Xudong Huang
Journal:  Mol Neurodegener       Date:  2009-01-28       Impact factor: 14.195
View more
  47 in total

1.  Neuroepigenomics: Resources, Obstacles, and Opportunities.

Authors:  John S Satterlee; Andrea Beckel-Mitchener; Roger Little; Dena Procaccini; Joni L Rutter; Amy C Lossie
Journal:  Neuroepigenetics       Date:  2015-01-01

2.  coMethDMR: accurate identification of co-methylated and differentially methylated regions in epigenome-wide association studies with continuous phenotypes.

Authors:  Lissette Gomez; Gabriel J Odom; Juan I Young; Eden R Martin; Lizhong Liu; Xi Chen; Anthony J Griswold; Zhen Gao; Lanyu Zhang; Lily Wang
Journal:  Nucleic Acids Res       Date:  2019-09-26       Impact factor: 16.971

3.  Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology.

Authors:  Lei Yu; Lori B Chibnik; Jingyun Yang; Cristin McCabe; Jishu Xu; Julie A Schneider; Philip L De Jager; David A Bennett
Journal:  Alzheimers Dement       Date:  2016-03-24       Impact factor: 21.566

Review 4.  Caloric restriction: beneficial effects on brain aging and Alzheimer's disease.

Authors:  Caroline Van Cauwenberghe; Charysse Vandendriessche; Claude Libert; Roosmarijn E Vandenbroucke
Journal:  Mamm Genome       Date:  2016-05-30       Impact factor: 2.957

Review 5.  Ageing, neurodegeneration and brain rejuvenation.

Authors:  Tony Wyss-Coray
Journal:  Nature       Date:  2016-11-10       Impact factor: 49.962

6.  Attenuation of neurobehavioral and neurochemical abnormalities in animal model of cognitive deficits of Alzheimer's disease by fermented soybean nanonutraceutical.

Authors:  Prakash Chandra Bhatt; Shruti Pathak; Vikas Kumar; Bibhu Prasad Panda
Journal:  Inflammopharmacology       Date:  2017-08-08       Impact factor: 4.473

7.  Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models.

Authors:  Sarah M Neuner; Lynda A Wilmott; Brian R Hoffmann; Khyobeni Mozhui; Catherine C Kaczorowski
Journal:  Behav Brain Res       Date:  2016-06-02       Impact factor: 3.332

8.  Structural Neuroimaging Genetics Interactions in Alzheimer's Disease.

Authors:  Seok Woo Moon; Ivo D Dinov; Jaebum Kim; Alen Zamanyan; Sam Hobel; Paul M Thompson; Arthur W Toga
Journal:  J Alzheimers Dis       Date:  2015       Impact factor: 4.472

9.  A Drosophila model of Huntington disease-like 2 exhibits nuclear toxicity and distinct pathogenic mechanisms from Huntington disease.

Authors:  Megan Krench; Richard W Cho; J Troy Littleton
Journal:  Hum Mol Genet       Date:  2016-06-10       Impact factor: 6.150

Review 10.  Early Life Epidemiology of Alzheimer's Disease--A Critical Review.

Authors:  Alon Seifan; Matthew Schelke; Yaa Obeng-Aduasare; Richard Isaacson
Journal:  Neuroepidemiology       Date:  2015-10-27       Impact factor: 3.282
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.