Literature DB >> 2515728

Heterophilic antibodies against rabbit serum causing falsely elevated gonadotropin levels.

L Berglund1, N G Holmberg.   

Abstract

Two cases are presented in which previously acquired antibodies against rabbits in the patient's serum caused falsely elevated hormonal levels in radio-immuno assays (RIA) based on rabbit antibodies to follicle-stimulating hormone (FSH) and human chorionic gonadotropin (hCG). The erroneous results led to unnecessary operative intervention and inconvenience for the patients.

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Year:  1989        PMID： 2515728     DOI： 10.3109/00016348909028676

Source DB:  PubMed          Journal:  Acta Obstet Gynecol Scand        ISSN： 0001-6349            Impact factor:   3.636


  3 in total

1.  Prevalence and isotypic complexity of the anti-Chinese hamster ovary host cell protein antibodies in normal human serum.

Authors:  Li Xue; Rasheeda Johnson; Boris Gorovits
Journal:  AAPS J       Date:  2009-12-15       Impact factor: 4.009

2.  Characterization of canine anti-mouse antibodies highlights that multiple strategies are needed to combat immunoassay interference.

Authors:  Daniel Bergman; Anders Larsson; Helene Hansson-Hamlin; Emma Åhlén; Bodil Ström Holst
Journal:  Sci Rep       Date:  2019-10-10       Impact factor: 4.379

Review 3.  Hormone Immunoassay Interference: A 2021 Update.

Authors:  Khaldoun Ghazal; Severine Brabant; Dominique Prie; Marie-Liesse Piketty
Journal:  Ann Lab Med       Date:  2022-01-01       Impact factor: 3.464
  3 in total

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