E Twizeyimana1, E Pichard2, F Lunel-Fabiani3, S Fanello2, S J De Martino4. 1. Laboratoire de virologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9 France; Service des maladies infectieuses et tropicales, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France; CNR des Borrelia, hôpitaux universitaires de Strasbourg, 1, rue Koeberlé, 67000 Strasbourg, France. Electronic address: eterne.twizeyimana@chru-strasbourg.fr. 2. Service des maladies infectieuses et tropicales, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France. 3. Laboratoire de virologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9 France. 4. CNR des Borrelia, hôpitaux universitaires de Strasbourg, 1, rue Koeberlé, 67000 Strasbourg, France.
Abstract
INTRODUCTION: Lyme borreliosis (LB) is an emerging arthropod-borne disease the diagnosis of which is made on clinical and biological data. We assessed the Angers University Hospital physicians' management of LB, in case of positive serology, and estimated their compliance to European recommendations (EUCALB). METHODS: We retrospectively included 75 cases with positive ELISA serologies confirmed by Western-Blot, performed at the Angers University Hospital between 2008 and 2012. RESULTS AND DISCUSSION: There were 4 cases of early localized phase, 26 of early-disseminated phase (including 17 cases of neuroborreliosis), and one case of late phase. The curative management complied with EUCALB guidelines in 28 cases out of 31. CONCLUSION: Serology remains a reference diagnostic tool for LB, as long as the practitioner is aware of the main clinical and biological criteria.
INTRODUCTION:Lyme borreliosis (LB) is an emerging arthropod-borne disease the diagnosis of which is made on clinical and biological data. We assessed the Angers University Hospital physicians' management of LB, in case of positive serology, and estimated their compliance to European recommendations (EUCALB). METHODS: We retrospectively included 75 cases with positive ELISA serologies confirmed by Western-Blot, performed at the Angers University Hospital between 2008 and 2012. RESULTS AND DISCUSSION: There were 4 cases of early localized phase, 26 of early-disseminated phase (including 17 cases of neuroborreliosis), and one case of late phase. The curative management complied with EUCALB guidelines in 28 cases out of 31. CONCLUSION: Serology remains a reference diagnostic tool for LB, as long as the practitioner is aware of the main clinical and biological criteria.